645 Ventures

645 Ventures is a New York City-based venture capital firm that specializes in partnering with exceptional founders at the Seed and Series A stages, with a strategic focus on building companies that can scale significantly into the growth stage. The firm is known for its data-driven investment approach and its comprehensive 'Platform' support, which provides portfolio companies with resources and expertise beyond just capital, including talent acquisition, business development, and strategic guidance.

The firm primarily invests in companies within the SaaS, infrastructure, and consumer technology sectors, demonstrating a keen interest in disruptive technologies and business models. Their investment thesis emphasizes identifying early-stage companies with strong product-market fit and significant potential for long-term growth. They aim to be a lead or co-lead investor, actively participating in the strategic development of their portfolio companies.

645 Ventures has demonstrated substantial growth in its investment capacity, evidenced by the closing of its seventh fund, Fund VII, in early 2024, which raised a total of $500 million. This fund is strategically split into a $300 million early-stage fund dedicated to Seed and Series A investments, and a $200 million growth fund for follow-on investments in their most promising portfolio companies. This structure allows them to support companies from their initial stages through significant growth milestones.

Their typical initial investment for a promising Seed round can start around $1 million, while for a Series A lead, their first check can extend up to $15 million, reflecting their commitment to substantial early-stage backing. With a portfolio that includes investments in over 100 companies, 645 Ventures has established itself as an active and impactful player in the early-stage venture capital landscape, consistently seeking to back the next generation of iconic technology companies.