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BioAdvance

North America, Pennsylvania, United States, Philadelphia

Description

BioAdvance is a prominent Pennsylvania-based venture capital firm dedicated to fostering innovation within the life sciences sector. Operating as an evergreen fund, it strategically invests in early-stage companies across the Mid-Atlantic region, specifically targeting promising ventures in Pennsylvania, New Jersey, and Delaware. The firm's investment scope spans a broad range of life sciences sub-sectors, including therapeutics, diagnostics, medical devices, research tools, and digital health solutions.

BioAdvance focuses on companies from the discovery phase through to clinical proof-of-concept, providing crucial capital and support during critical early development stages. Their investment philosophy is geared towards identifying and nurturing groundbreaking technologies and scientific advancements that have the potential to significantly impact healthcare and beyond. This targeted approach allows them to build a specialized portfolio aligned with the region's strong life sciences ecosystem.

Financially, BioAdvance manages a $50 million evergreen fund, which provides a sustainable capital base for its ongoing investment activities. For initial investments, the firm typically writes checks ranging from $500,000 to $1,500,000. Demonstrating a long-term commitment to its portfolio companies, BioAdvance is prepared to invest up to $3,000,000 over the lifetime of a single company, supporting their growth and development through subsequent funding rounds as they achieve key milestones. This patient capital approach underscores their dedication to the success of their portfolio companies and the advancement of the life sciences industry in the region.

Investor Profile

BioAdvance has backed more than 197 startups, with 2 new investments in the last 12 months alone. The firm has led 24 rounds, about 12% of its total and boasts 19 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Seed, Series Unknown, Series A rounds (top funding stages).
  • Majority of deals are located in United States, Canada, Russian Federation.
  • Strong thematic focus on Biotechnology, Health Care, Pharmaceutical.
  • Typical check size: $500K – $1.5M.

Stage Focus

  • Seed (49%)
  • Series Unknown (27%)
  • Series A (10%)
  • Series B (5%)
  • Debt Financing (4%)
  • Series C (2%)
  • Series D (2%)
  • Post Ipo Equity (1%)
  • Pre Seed (1%)

Country Focus

  • United States (97%)
  • Canada (1%)
  • Russian Federation (1%)

Industry Focus

  • Biotechnology
  • Health Care
  • Pharmaceutical
  • Medical
  • Biopharma
  • Health Diagnostics
  • Therapeutics
  • Analytics
  • Information Technology
  • Oncology
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does BioAdvance frequently co-invest with?

Ben Franklin Technology Partners of Southeastern Pennsylvania
North America, Pennsylvania, United States, Philadelphia
Co-Investments: 8
BroadOak Capital Partners
North America, Maryland, United States, Bethesda
Co-Investments: 3
Birchmere Ventures
North America, Pennsylvania, United States, Pittsburgh
Co-Investments: 3
Agent Capital
North America, Massachusetts, United States, Cambridge
Co-Investments: 3
Samsara BioCapital
North America, California, United States, Palo Alto
Co-Investments: 3
Safeguard Scientifics
North America, Pennsylvania, United States, Radnor
Co-Investments: 5
Bay City Capital
North America, California, United States, San Francisco
Co-Investments: 3
Biotechnology Value Fund
North America, California, United States, San Francisco
Co-Investments: 3
Dreamit Ventures
North America, Pennsylvania, United States, Philadelphia
Co-Investments: 4
Research Corporation Technologies
North America, Arizona, United States, Tucson
Co-Investments: 3

Which angels does BioAdvance often collaborate with?

SB
North America, Pennsylvania, United States, Philadelphia
Shared Deals: 2
PM
North America, New York, United States, New York
Shared Deals: 1
T"
North America, Wisconsin, United States, Madison
Shared Deals: 1
Shared Deals: 1
BF
North America, Colorado, United States, Boulder
Shared Deals: 1
Sohil Shah
Asia, Maharashtra, India, Mumbai
Shared Deals: 1
JH
North America, Illinois, United States, Chicago
Shared Deals: 1
FA
North America, Maryland, United States, Baltimore
Shared Deals: 1
Shared Deals: 1
Shared Deals: 1

What are some of recent deals done by BioAdvance?

Palvella Therapeutics

Wayne, Pennsylvania, United States

Palvella Therapeutics focuses on relentlessly and selflessly serving abandoned patient populations with therapies.

BiotechnologyHealth CareLife ScienceTherapeutics
Post Ipo EquityDec 13, 2024

Tolerance Bio is a biopharmaceutical company focused on manipulating immune tolerance via the thymus.

Biotechnology
SeedOct 15, 2024
Amount Raised: $20,200,000
Vittoria Biotherapeutics

Philadelphia, Pennsylvania, United States

Vittoria Biotherapeutics is a gene-edited cell therapeutics company.

BioinformaticsBiotechnologyTest and Measurement
Series UnknownNov 14, 2023
Amount Raised: $15,000,000
KayoThera

Princeton, New Jersey, United States

KayoThera develops therapeutics used to cure late-stage and metastatic cancers.

BiotechnologyHealth CareMedical
Series AJul 19, 2023
Amount Raised: $5,200,000
Palvella Therapeutics

Wayne, Pennsylvania, United States

Palvella Therapeutics focuses on relentlessly and selflessly serving abandoned patient populations with therapies.

BiotechnologyHealth CareLife ScienceTherapeutics
Series DJan 5, 2023
Amount Raised: $37,700,000
Senzo

San Francisco, California, United States

Senzo is a deep-tech bio-med company developing testing products and IP.

BiotechnologyHealth CareHealth DiagnosticsInformation Technology
SeedDec 12, 2022
Amount Raised: $1,900,000
Innervace

Philadelphia, Pennsylvania, United States

Innvervace develops regenerative therapy solutions for neurodegenerative disorders.

BiotechnologyHealth CareMedicalNeuroscience
Series ASep 8, 2022
Amount Raised: $40,000,000
Senzo

San Francisco, California, United States

Senzo is a deep-tech bio-med company developing testing products and IP.

BiotechnologyHealth CareHealth DiagnosticsInformation Technology
SeedJul 21, 2022
Amount Raised: $2,000,000
Halo Labs

Philadelphia, Pennsylvania, United States

Halo Labs is a biotechnology company that specializes in analytical instrumentation and biopharma.

AnalyticsBiopharmaBiotechnologyHealth DiagnosticsPharmaceutical
Series CJul 11, 2022
Amount Raised: $6,999,990
KayoThera

Princeton, New Jersey, United States

KayoThera develops therapeutics used to cure late-stage and metastatic cancers.

BiotechnologyHealth CareMedical
Series AMar 16, 2022
Amount Raised: $8,000,000