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Casdin Capital

North America, New York, United States, New York

Description

Casdin Capital is a New York-based investment firm distinguished by its fundamental research-driven approach to the life sciences and healthcare sectors. Founded by Eli Casdin, the firm employs a unique hybrid investment model, deploying capital across both public and private markets. This dual focus allows Casdin Capital to engage with companies at various stages of their lifecycle, from nascent private ventures to established public entities, providing a comprehensive and flexible investment strategy within the complex biotech and healthcare landscape.

The firm's investment philosophy is deeply rooted in scientific and industry expertise, aiming to identify and support companies poised for significant innovation and growth. Casdin Capital is known for its substantial capital deployment, evidenced by the closing of its latest fund in March 2022, which raised an impressive $1.1 billion. This significant capital base enables the firm to make meaningful investments, with typical first checks for private companies ranging from $25 million to $100 million. They often take on lead or co-lead investor roles in funding rounds, demonstrating a commitment to actively shaping the trajectory of their portfolio companies.

Casdin Capital's portfolio spans a wide array of life science sub-sectors, including genomics, cell and gene therapy, drug discovery platforms, and diagnostics. They seek out companies that are leveraging cutting-edge science and technology to address unmet medical needs or revolutionize healthcare delivery. Their strategic involvement extends beyond capital, often providing operational and strategic guidance to help founders and management teams scale their innovations. This hands-on approach, combined with their deep sector knowledge, positions Casdin Capital as a significant player in advancing the life sciences ecosystem.

Investor Profile

Casdin Capital has backed more than 218 startups, with 5 new investments in the last 12 months alone. The firm has led 34 rounds, about 16% of its total and boasts 73 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series B, Series A, Series C rounds (top funding stages).
  • Majority of deals are located in United States, France, United Kingdom.
  • Strong thematic focus on Biotechnology, Health Care, Therapeutics.
  • Typical check size: $25M – $100M.

Stage Focus

  • Series B (31%)
  • Series A (21%)
  • Series C (15%)
  • Series Unknown (9%)
  • Post Ipo Equity (8%)
  • Series D (6%)
  • Series E (4%)
  • Seed (3%)
  • Series F (1%)
  • Debt Financing (1%)

Country Focus

  • United States (88%)
  • France (3%)
  • United Kingdom (2%)
  • Switzerland (1%)
  • Canada (1%)
  • China (1%)
  • The Netherlands (1%)

Industry Focus

  • Biotechnology
  • Health Care
  • Therapeutics
  • Medical
  • Life Science
  • Genetics
  • Pharmaceutical
  • Health Diagnostics
  • Biopharma
  • Software
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Casdin Capital frequently co-invest with?

Nextech Invest
Europe, Zurich, Switzerland, Zürich
Co-Investments: 23
CA
North America, Massachusetts, United States, Boston
Co-Investments: 26
Alexandria Venture Investments
North America, California, United States, Pasadena
Co-Investments: 29
Google Ventures
North America, California, United States, Mountain View
Co-Investments: 48
Third Rock Ventures
North America, Massachusetts, United States, Boston
Co-Investments: 26
Perceptive Advisors
North America, New York, United States, New York
Co-Investments: 26
Redmile Group
North America, California, United States, San Francisco
Co-Investments: 21
Section 32
North America, California, United States, San Diego
Co-Investments: 22
Invus
North America, New York, United States, New York
Co-Investments: 24
Fidelity
North America, Massachusetts, United States, Boston
Co-Investments: 30

Which angels does Casdin Capital often collaborate with?

WG
North America, California, United States, San Francisco
Shared Deals: 1
RS
North America, California, United States, San Francisco
Shared Deals: 1
CD
North America, California, United States
Shared Deals: 1
MB
North America, California, United States, San Francisco
Shared Deals: 1
BG
North America, Washington, United States, Seattle
Shared Deals: 3
MA
North America, California, United States, San Francisco
Shared Deals: 1
AW
North America, California, United States, San Francisco
Shared Deals: 4
AG
North America, Colorado, United States, Denver
Shared Deals: 1
FB
North America, New York, United States, New York
Shared Deals: 3
BB
North America, California, United States, San Francisco
Shared Deals: 2

What are some of recent deals done by Casdin Capital?

Auron Therapeutics

Newton, Massachusetts, United States

Auron aims to cure cancer therapeutics from cell killing to transformation of malignant cells into more normal functioning cells.

BiotechnologyHealth CareTherapeutics
Series BFeb 4, 2025
Amount Raised: $27,000,000
Leyden Labs

Amsterdam, Noord-Holland, The Netherlands

Leyden Labs provides a platform that targets commonalities of viral families to protect humanity from known and future viruses.

BiotechnologyLife ScienceTherapeutics
Series BJan 9, 2025
Amount Raised: $70,000,000
nChroma Bio

Boston, Massachusetts, United States

nChroma Bio is a cutting-edge biotechnology business that is developing targeted in vivo delivery systems as well as best-in-class cargo.

BiotechnologyMedicalProduct Research
Series UnknownDec 11, 2024
Amount Raised: $75,000,000
Neurogene

New York, New York, United States

Neurogene is a developer of genetic medicines intended to improve patient outcomes for neurological disorders.

Biotechnology
Post Ipo EquityNov 4, 2024
Amount Raised: $200,000,000
Idrx

Plymouth, Massachusetts, United States

Idrx is a clinical-stage biopharmaceutical company dedicated to transforming cancer treatment.

BiotechnologyLife ScienceOncologyProduct Research
Series BAug 7, 2024
Amount Raised: $120,000,000
Scorpion Therapeutics

Boston, Massachusetts, United States

Scorpion Therapeutics is a clinical-stage oncology company that specializes in precision medicine for cancer patients.

BiotechnologyHealth CareLife ScienceOncologyPrecision Medicine
Series CJul 16, 2024
Amount Raised: $150,000,000
TMRW Life Sciences

New York, New York, United States

TMRW Life Sciences provides an integrated platform for automated, software-guided cryospecimen management.

BiotechnologyHealth CareLife ScienceSoftware
Series DJul 12, 2024
Amount Raised: $28,172,940
BridgeBio Oncology Therapeutics

Palo Alto, California, United States

BridgeBio Oncology Therapeutics operates as a biopharmaceutical company.

BiopharmaTherapeutics
Series UnknownMay 2, 2024
Amount Raised: $200,000,000
Century Therapeutics

Philadelphia, Pennsylvania, United States

Century Therapeutics is a biotechnology company that develops cell therapies for hematological and solid tumor malignancies.

BiotechnologyHealth CareHealth Diagnostics
Post Ipo EquityApr 11, 2024
Amount Raised: $60,000,000
Avidity Biosciences

San Diego, California, United States

Avidity Biosciences is a biotechnology company that develops oligonucleotide-based therapies for its patients.

BiotechnologyHealth CareLife SciencePharmaceuticalTherapeutics
Post Ipo EquityFeb 29, 2024
Amount Raised: $400,000,000