Early Stage Partners logo

Early Stage Partners

North America, Ohio, United States, Cleveland

Description

Early Stage Partners is a Cleveland, Ohio-based venture capital firm established in 2000, dedicated to providing early-stage financing to entrepreneurial companies primarily within the Midwest region. The firm positions itself as a crucial capital provider for nascent businesses, aiming to foster innovation and growth in its local ecosystem and beyond. Its strategic location in Cleveland allows it to tap into the burgeoning tech and life science sectors emerging from the region's strong academic and research institutions.

The firm's investment thesis centers on identifying high-potential startups across several key sectors, including technology, life sciences, advanced materials, and cleantech. Early Stage Partners is particularly interested in companies that demonstrate strong intellectual property, scalable business models, and experienced management teams. While its primary geographic focus is the Midwest, especially Ohio, the firm evaluates opportunities that align with its sector expertise and potential for significant returns, contributing to the development of a robust regional innovation economy.

Early Stage Partners has a history of deploying capital through multiple funds. Its second fund, Early Stage Partners II, closed in 2006 with commitments totaling $30 million, building upon the success of its initial $20 million fund. This capital is typically deployed in initial investments ranging from $250,000 to $1 million, providing essential seed and Series A funding to promising ventures. The firm also demonstrates a commitment to its portfolio companies through follow-on investments, potentially investing up to $3 million over the life of a company as it achieves key milestones and scales its operations. This patient capital approach underscores their long-term partnership strategy with founders.

Investor Profile

Early Stage Partners has backed more than 38 startups, with 0 new investments in the last 12 months alone. The firm has led 5 rounds, about 13% of its total and boasts 7 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series B, Series A, Series C rounds (top funding stages).
  • Majority of deals are located in United States.
  • Strong thematic focus on Health Care, Software, Medical Device.
  • Typical check size: $250K – $1M.

Stage Focus

  • Series B (34%)
  • Series A (32%)
  • Series C (18%)
  • Series Unknown (8%)
  • Series D (8%)

Country Focus

  • United States (100%)

Industry Focus

  • Health Care
  • Software
  • Medical Device
  • Biotechnology
  • Saas
  • Medical
  • Electronics
  • Enterprise Software
  • Information Technology
  • Manufacturing
circle-line
FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Early Stage Partners frequently co-invest with?

Reservoir Venture Partners
North America, Ohio, United States, Westerville
Co-Investments: 9
JumpStart
North America, Ohio, United States, Cleveland
Co-Investments: 2
Draper Associates
North America, California, United States, San Mateo
Co-Investments: 3
West Capital Advisors
North America, Illinois, United States, Chicago
Co-Investments: 4
Venture Investors
North America, Wisconsin, United States, Madison
Co-Investments: 3
Industrial Technology Ventures
North America, Georgia, United States, Alpharetta
Co-Investments: 4
Morgenthaler Ventures
North America, California, United States, Menlo Park
Co-Investments: 3
North Coast Ventures
North America, Ohio, United States, Cleveland
Co-Investments: 4
Draper Triangle
North America, Pennsylvania, United States, Pittsburgh
Co-Investments: 8
Fletcher Spaght, Inc.
North America, Massachusetts, United States, Boston
Co-Investments: 4

What are some of recent deals done by Early Stage Partners?

HistoSonics

Plymouth, Minnesota, United States

HistoSonics specializes in developing non-invasive medical devices, interventional radiology, and surgical robotics.

Health CareMedicalMedical Device
Series BMar 13, 2017
Amount Raised: $8,260,313
OnShift

Cleveland, Ohio, United States

OnShift delivers cloud-based human capital management software and proactive services to solve everyday workforce challenges in healthcare.

Cloud ComputingHealth CareHospitalSaaSSoftware
Series DApr 13, 2016
Amount Raised: $18,000,000
Amplifinity

Ann Arbor, Michigan, United States

Amplifinity develops referral software that automates the referral tracking and management of B2B customer and partner referral programs.

Brand MarketingEnterprise SoftwareLead GenerationMarketing AutomationSaaSSoftware
Series BMar 18, 2014
Amount Raised: $7,000,000
OnShift

Cleveland, Ohio, United States

OnShift delivers cloud-based human capital management software and proactive services to solve everyday workforce challenges in healthcare.

Cloud ComputingHealth CareHospitalSaaSSoftware
Series CFeb 3, 2014
Amount Raised: $7,000,000
Juventas Therapeutics

Cleveland, Ohio, United States

Juventas Therapeutics is a clinical-stage biotechnology company developing regenerative therapies to treat life threatening diseases.

BiotechnologyHealth CareLife ScienceMedicalMedical DeviceTherapeutics
Series BJul 16, 2012
Amount Raised: $22,200,000
OnShift

Cleveland, Ohio, United States

OnShift delivers cloud-based human capital management software and proactive services to solve everyday workforce challenges in healthcare.

Cloud ComputingHealth CareHospitalSaaSSoftware
Series BMay 2, 2012
Amount Raised: $4,483,008
LineStream Technologies

Cleveland, Ohio, United States

LineStream Technologies provides control technology and software solutions that improve the performance of automated products and processes.

AutomotiveCleanTechElectronicsEnergy EfficiencyInformation TechnologyManufacturingSoftwareTelecommunications
Series BMar 12, 2012
Amount Raised: $5,000,000
CytoPherx

Ann Arbor, Michigan, United States

CytoPherx is a medical device company offering a proprietary selective cytopheresis sytem for inflammation-based diseases and conditions.

Health CareLife ScienceMedical Device
Series CJan 4, 2012
Amount Raised: $34,000,000
Amplifinity

Ann Arbor, Michigan, United States

Amplifinity develops referral software that automates the referral tracking and management of B2B customer and partner referral programs.

Brand MarketingEnterprise SoftwareLead GenerationMarketing AutomationSaaSSoftware
Series ADec 9, 2011
Amount Raised: $3,600,000
SironRX Therapeutics

Cleveland, Ohio, United States

SironRX is developing novel therapies that promote dermal wound repair and reduce scarring.

BiotechnologyMedicalTherapeutics
Series AAug 16, 2011
Amount Raised: $3,400,000