Lewis & Clark AgriFood logo

Lewis & Clark AgriFood

North America, Missouri, United States, St Louis

Description

Lewis & Clark AgriFood is a prominent St. Louis-based venture capital firm dedicated to investing in the rapidly evolving food and agriculture technology sectors. Established in 2016, the firm has quickly positioned itself as a key player in the agrifood tech ecosystem, focusing on companies that are driving innovation across the value chain. Their investment thesis centers on supporting growth-stage businesses that address critical challenges and opportunities in sustainable agriculture, food technology, animal health, and supply chain efficiency.

Investor Profile

Lewis & Clark AgriFood has backed more than 23 startups, with 3 new investments in the last 12 months alone. The firm has led 14 rounds, about 61% of its total and boasts 0 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series B, Series A, Series Unknown rounds (top funding stages).
  • Majority of deals are located in United States, Canada.
  • Strong thematic focus on Agriculture, Biotechnology, Artificial Intelligence (AI).
  • Typical check size: $5M – $20M.

Stage Focus

  • Series B (57%)
  • Series A (17%)
  • Series Unknown (13%)
  • Convertible Note (4%)
  • Debt Financing (4%)
  • Series C (4%)

Country Focus

  • United States (96%)
  • Canada (4%)

Industry Focus

  • Agriculture
  • Biotechnology
  • Artificial Intelligence (Ai)
  • Agtech
  • Farming
  • Chemical
  • Industrial
  • Manufacturing
  • Computer
  • Food And Beverage
circle-line
FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Lewis & Clark AgriFood frequently co-invest with?

BV
North America, Missouri, United States, Chesterfield
Co-Investments: 3
S2G Ventures
North America, Illinois, United States, Chicago
Co-Investments: 4
Cavallo Ventures
North America, California, United States, San Francisco
Co-Investments: 4
50 South Capital
North America, Illinois, United States, Chicago
Co-Investments: 2
Innova Memphis
North America, Tennessee, United States, Memphis
Co-Investments: 3
BI
North America, California, United States, San Francisco
Co-Investments: 3
Germin8 Ventures
North America, Illinois, United States, Chicago
Co-Investments: 4
Alpha Impact Investment Management Partners
North America, California, United States, Palo Alto
Co-Investments: 2
Continental Grain Company
North America, New York, United States, New York
Co-Investments: 4
Ospraie Ag Sciences
North America, New York, United States, New York
Co-Investments: 3

Which angels does Lewis & Clark AgriFood often collaborate with?

BS
North America, New York, United States, New York
Shared Deals: 1

What are some of recent deals done by Lewis & Clark AgriFood?

IUNU

Seattle, Washington, United States

IUNU is an industrial computer vision company that connects plants, facilities, and people through a single interface.

AgricultureArtificial Intelligence (AI)ComputerIndustrialRenewable Energy
Series BApr 15, 2025
Amount Raised: $20,000,000
AgroSpheres

Charlottesville, Virginia, United States

AgroSpheres develops novel technologies that aim to set a new standard for bio-based delivery of active ingredients.

AgricultureBiotechnologyChemicalIndustrial
Series BSep 30, 2024
Amount Raised: $12,000,000
Arzeda

Seattle, Washington, United States

Arzeda is a protein design company that creates and manufactures proteins and enzymes for pharmaceuticals and industrial chemicals.

Artificial Intelligence (AI)BiotechnologyChemicalManufacturing
Series CSep 17, 2024
Amount Raised: $38,000,000
AgroSpheres

Charlottesville, Virginia, United States

AgroSpheres develops novel technologies that aim to set a new standard for bio-based delivery of active ingredients.

AgricultureBiotechnologyChemicalIndustrial
Series BNov 27, 2023
Amount Raised: $3,000,000
Lingrove

San Rafael, California, United States

Lingrove manufactures natural fiber composites from plant-based fibers and resins using a proprietary process and adaptable platform.

Advanced MaterialsConstructionManufacturingMechanical Engineering
Series BNov 20, 2023
Amount Raised: $10,499,997
Bushel

Fargo, North Dakota, United States

Bushel focuses on software technology solutions for farmers, grain buyers, ag retailers, protein producers, and food industries.

AgTechAppsComputeriOSSoftware
Series UnknownJul 13, 2023
Amount Raised: $26,000,000
P2 Science

Woodbridge, Connecticut, United States

P2 Science develops a bio-refining process for the conversion of biomass such as vegetable oils into high-value specialty chemicals.

BiotechnologyChemicalRenewable Energy
Series UnknownFeb 23, 2023
Stony Creek Colors

Springfield, Tennessee, United States

Stony Creek Colors is engaged in the production of bio-based dyes together with farmers, mills, and brands.

AgricultureAgTechFarming
Series BDec 1, 2022
Amount Raised: $4,800,000
AgroSpheres

Charlottesville, Virginia, United States

AgroSpheres develops novel technologies that aim to set a new standard for bio-based delivery of active ingredients.

AgricultureBiotechnologyChemicalIndustrial
Series BOct 20, 2022
Amount Raised: $22,153,089
Brightseed

San Francisco, California, United States

Brightseed uses artificial intelligence and machine learning to discover the potential of plant compounds for various applications.

Artificial Intelligence (AI)BiotechnologyFood and BeveragePharmaceuticalWellness
Series BMay 9, 2022
Amount Raised: $68,000,000