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Sanderling Ventures

North America, California, United States, San Mateo

Description

Sanderling Ventures, established in 1979 and headquartered in San Mateo, California, is a pioneering venture capital firm exclusively dedicated to the biomedical sector. With a rich history spanning over four decades, Sanderling distinguishes itself through a hands-on, company-building approach, often participating in the inception and early management of new biotechnology, pharmaceutical, medical device, and diagnostic companies. This deep operational involvement allows them to nurture nascent ideas from concept to commercialization, focusing on ventures that address significant unmet medical needs.

The firm's investment philosophy centers on identifying and developing groundbreaking scientific innovations. Sanderling provides crucial seed and early-stage capital, often acting as a lead investor in initial funding rounds. Their team comprises seasoned professionals with extensive scientific, medical, and entrepreneurial backgrounds, enabling them to offer strategic guidance and operational support to their portfolio companies. This active engagement is a hallmark of their strategy, aiming to de-risk early-stage development and accelerate growth.

Sanderling Ventures has consistently raised substantial funds to support its investment activities. For instance, the firm closed its tenth fund, Sanderling Ventures X, at $200 million in 2018, following its ninth fund, Sanderling Ventures IX, which also closed at $200 million in 2013. These significant capital pools enable Sanderling to deploy substantial first checks, typically ranging from $5 million to $20 million, depending on the stage and specific needs of the company. They are known for their capacity to provide follow-on funding throughout a company's lifecycle, demonstrating a long-term commitment to their portfolio. Their enduring presence and specialized focus have cemented their reputation as a key player in the biomedical venture capital landscape.

Investor Profile

Sanderling Ventures has backed more than 96 startups, with 1 new investments in the last 12 months alone. The firm has led 23 rounds, about 24% of its total and boasts 19 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series C, Series B, Series A rounds (top funding stages).
  • Majority of deals are located in United States, Canada, India.
  • Strong thematic focus on Health Care, Biotechnology, Pharmaceutical.
  • Typical check size: $5M – $20M.

Stage Focus

  • Series C (24%)
  • Series B (21%)
  • Series A (20%)
  • Series D (15%)
  • Series Unknown (11%)
  • Debt Financing (3%)
  • Series E (3%)
  • Post Ipo Equity (1%)
  • Series F (1%)
  • Seed (1%)

Country Focus

  • United States (92%)
  • Canada (7%)
  • India (1%)

Industry Focus

  • Health Care
  • Biotechnology
  • Pharmaceutical
  • Medical
  • Medical Device
  • Therapeutics
  • Information Technology
  • Life Science
  • Genetics
  • Health Diagnostics
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Sanderling Ventures frequently co-invest with?

Qualcomm Ventures
North America, California, United States, San Diego
Co-Investments: 5
CV
North America, Massachusetts, United States, Boston
Co-Investments: 4
MV
North America, California, United States, San Diego
Co-Investments: 7
PrairieGold Venture Partners
North America, South Dakota, United States, Sioux Falls
Co-Investments: 4
Alta Partners
North America, Mississippi, United States, Jackson
Co-Investments: 9
Thomas, McNerney & Partners
North America, Connecticut, United States, Stamford
Co-Investments: 4
Mayo Clinic Ventures
North America, Minnesota, United States, Rochester
Co-Investments: 6
Clarus Ventures
North America, Massachusetts, United States, Cambridge
Co-Investments: 5
Asset Management Ventures (AMV)
North America, California, United States, Palo Alto
Co-Investments: 6
Intel Capital
North America, California, United States, Santa Clara
Co-Investments: 5

Which angels does Sanderling Ventures often collaborate with?

Shared Deals: 1
SH
North America, California, United States
Shared Deals: 1
Shared Deals: 1
Shared Deals: 1
Shared Deals: 1
Shared Deals: 1
Shared Deals: 1

What are some of recent deals done by Sanderling Ventures?

Glycomine

San Francisco, California, United States

Glycomine is an early-stage biotech working on replacement therapies for rare diseases.

BiotechnologyPharmaceuticalTherapeutics
Series CApr 16, 2025
Amount Raised: $115,000,000
CalciMedica

La Jolla, California, United States

CalciMedica is engaged in the discovery and development of small molecule drugs for the treatment of inflammatory and autoimmune disorders.

Health CareInformation TechnologyLife Science
Post Ipo EquityJan 22, 2024
Amount Raised: $55,000,000
Glycomine

San Francisco, California, United States

Glycomine is an early-stage biotech working on replacement therapies for rare diseases.

BiotechnologyPharmaceuticalTherapeutics
Series BJun 23, 2021
Amount Raised: $35,000,000
CalciMedica

La Jolla, California, United States

CalciMedica is engaged in the discovery and development of small molecule drugs for the treatment of inflammatory and autoimmune disorders.

Health CareInformation TechnologyLife Science
Series DMar 11, 2021
Amount Raised: $21,000,000
CalciMedica

La Jolla, California, United States

CalciMedica is engaged in the discovery and development of small molecule drugs for the treatment of inflammatory and autoimmune disorders.

Health CareInformation TechnologyLife Science
Series CMay 22, 2020
Amount Raised: $15,000,000
ViaCyte

San Diego, California, United States

ViaCyte is a preclinical therapeutic company specializing in regenerative medicine therapies for diabetes.

BiotechnologyDiabetesHealth CareMedicalTherapeutics
Series DMar 20, 2020
Amount Raised: $32,645,780
Glycomine

San Francisco, California, United States

Glycomine is an early-stage biotech working on replacement therapies for rare diseases.

BiotechnologyPharmaceuticalTherapeutics
Series BAug 7, 2019
Amount Raised: $33,000,000
ViaCyte

San Diego, California, United States

ViaCyte is a preclinical therapeutic company specializing in regenerative medicine therapies for diabetes.

BiotechnologyDiabetesHealth CareMedicalTherapeutics
Series DNov 29, 2018
Amount Raised: $80,000,000
Metavention

Eden Prairie, Minnesota, United States

Metavention develops medical devices to help with interventional therapies for high blood pressure and other metabolic diseases.

BiotechnologyDiabetesHealth Care
Series CJan 8, 2018
Amount Raised: $65,000,000
SpecificiT Pharma

Montréal, Quebec, Canada

A privately held biopharmaceutical company.

BiotechnologyHealth CarePharmaceutical
SeedSep 11, 2017