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SightLine Partners

North America, Minnesota, United States, Minneapolis

Description

SightLine Partners is a Minneapolis-based venture capital firm specializing in late-stage medical technology companies. The firm distinguishes itself by focusing exclusively on the healthcare sector, specifically targeting companies involved in medical devices, diagnostics, and specialty pharmaceuticals. Their investment strategy is centered on providing growth equity to businesses that have already achieved significant product validation and are poised for commercial expansion or strategic M&A activities. This targeted approach allows SightLine Partners to leverage deep industry expertise and a robust network within the medical technology landscape.

The firm primarily invests in companies that have demonstrated strong market traction and are seeking capital to accelerate commercialization, expand product lines, or pursue strategic acquisitions. They typically engage with businesses that are beyond the early development stages, focusing on those with proven products and revenue streams. A notable aspect of their funding history includes the closing of SightLine Healthcare Fund IV in 2021, which secured $300 million in capital commitments. Prior to this, SightLine Healthcare Fund III closed in 2017 with $250 million, illustrating a consistent growth in their fund sizes and investor confidence.

SightLine Partners' typical first check sizes reflect their late-stage, growth equity focus. While specific figures can vary based on the opportunity, their investments generally range from approximately $10 million to $40 million. This substantial capital infusion is often coupled with strategic guidance, operational support, and access to their extensive industry network, aiming to accelerate the growth and market penetration of their portfolio companies. Their commitment extends beyond mere capital, as they actively partner with management teams to navigate complex regulatory environments, optimize commercialization strategies, and prepare for potential exit events, solidifying their role as a value-added investor in the medical technology space.

Investor Profile

SightLine Partners has backed more than 22 startups, with 0 new investments in the last 12 months alone. The firm has led 2 rounds, about 9% of its total and boasts 7 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series D, Series C, Series F rounds (top funding stages).
  • Majority of deals are located in United States.
  • Strong thematic focus on Health Care, Medical Device, Biotechnology.
  • Typical check size: $10M – $40M.

Stage Focus

  • Series D (23%)
  • Series C (23%)
  • Series F (18%)
  • Series E (9%)
  • Series I (5%)
  • Series B (5%)
  • Series G (5%)
  • Private Equity (5%)
  • Series Unknown (5%)
  • Series A (5%)

Country Focus

  • United States (100%)

Industry Focus

  • Health Care
  • Medical Device
  • Biotechnology
  • Medical
  • Health Diagnostics
  • Manufacturing
  • Therapeutics
  • Clinical Trials
  • Data Integration
  • Web Browsers
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does SightLine Partners frequently co-invest with?

InterWest Partners
North America, California, United States, Menlo Park
Co-Investments: 2
CRG
North America, Texas, United States, Houston
Co-Investments: 2
New Enterprise Associates
North America, California, United States, Menlo Park
Co-Investments: 6
Johnson & Johnson Development Corporation
North America, New Jersey, United States, New Brunswick
Co-Investments: 3
Frazier Healthcare Partners
North America, Washington, United States, Seattle
Co-Investments: 2
Split Rock Partners
North America, Minnesota, United States, Minneapolis
Co-Investments: 3
Morgenthaler Ventures
North America, California, United States, Menlo Park
Co-Investments: 3
Affinity Capital Management
North America, Minnesota, United States, Minneapolis
Co-Investments: 4
Gilde Healthcare
Europe, Utrecht, The Netherlands, Utrecht
Co-Investments: 3
Evidity Health Capital
North America, New York, United States, New York
Co-Investments: 3

What are some of recent deals done by SightLine Partners?

Magnolia Medical Technologies

Seattle, Washington, United States

Magnolia Medical Technologies is a device development company that focuses on improving the accuracy of diagnostic blood culture tests.

Health CareHealth DiagnosticsMedical Device
Private EquityFeb 16, 2022
Amount Raised: $46,000,000
Magnolia Medical Technologies

Seattle, Washington, United States

Magnolia Medical Technologies is a device development company that focuses on improving the accuracy of diagnostic blood culture tests.

Health CareHealth DiagnosticsMedical Device
Series CJan 30, 2019
Amount Raised: $20,000,000
Vapotherm

Exeter, New Hampshire, United States

Vapotherm is a medical device company that develops a mask-free respiratory support tool.

BiotechnologyHealth CareManufacturingMedical Device
Series DSep 1, 2018
Amount Raised: $10,000,000
EndoGastric Solutions

San Mateo, California, United States

EGS manufactures EsophyX technology is used to reconstruct the gastroesophageal valve in the TIF 2.0 procedure.

Health CareHealth DiagnosticsMedical Device
Series IJun 19, 2018
Amount Raised: $40,648,790
Earlens

Menlo Park, California, United States

Earlens is a medical technology company transforming the hearing experience with the only direct sound delivery system.

Health CareMedicalMedical Device
Series CJun 5, 2017
Amount Raised: $73,000,000
Monteris Medical

Plymouth, Minnesota, United States

Monteris Medical is a medical device venture that develops new technologies for the treatment of cancer.

BiotechnologyHealth CareMedicalMedical Device
Series CJun 1, 2017
Amount Raised: $26,600,000
Vapotherm

Exeter, New Hampshire, United States

Vapotherm is a medical device company that develops a mask-free respiratory support tool.

BiotechnologyHealth CareManufacturingMedical Device
Series DMay 25, 2017
Amount Raised: $45,000,000
Vapotherm

Exeter, New Hampshire, United States

Vapotherm is a medical device company that develops a mask-free respiratory support tool.

BiotechnologyHealth CareManufacturingMedical Device
Series CJul 13, 2015
Amount Raised: $20,000,000
Conventus Orthopaedics

Maple Grove, Minnesota, United States

Conventus Orthopaedics is a provider of a range of orthopedic and sports medicine services.

BiotechnologyHealth DiagnosticsMedical Device
Series ADec 2, 2014
Amount Raised: $24,000,000
Conventus Orthopaedics

Maple Grove, Minnesota, United States

Conventus Orthopaedics is a provider of a range of orthopedic and sports medicine services.

BiotechnologyHealth DiagnosticsMedical Device
Series UnknownOct 3, 2013
Amount Raised: $11,500,333