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UK Innovation & Science Seed Fund

Europe, Oxfordshire, United Kingdom, Harwell

Description

The UK Innovation & Science Seed Fund (UKISSF), formerly known as the Rainbow Seed Fund, is a prominent early-stage venture capital fund based in Harwell, United Kingdom. Established with a mission to commercialize groundbreaking science and engineering innovations, UKISSF operates as a £50 million fund managed by Future Planet Capital. Its unique mandate focuses on investing in spin-out companies emerging from the UK’s publicly funded research establishments, including institutions like STFC, NERC, BBSRC, Dstl, Fera, and the UK Atomic Energy Authority. This strategic alignment ensures that the fund targets ventures with deep technological roots and significant potential for societal and economic impact.

UKISSF's investment thesis centers on high-growth, technology-driven sectors critical to the future economy. The fund actively seeks opportunities across a diverse range of fields, including artificial intelligence, quantum technologies, space exploration, robotics, life sciences, net-zero solutions, and advanced materials. By concentrating on these areas, UKISSF aims to support the transformation of cutting-edge research into viable commercial enterprises, fostering innovation and economic growth within the UK's scientific ecosystem. The fund's commitment extends beyond initial capital, often providing strategic guidance and leveraging its network to support portfolio companies through their growth journey.

Since its inception in 2002, UKISSF has built a robust portfolio and a strong track record of success. The fund typically provides initial investments ranging from £250,000 to £1 million, with the capacity for follow-on funding to support the continued development and scaling of its portfolio companies. To date, UKISSF has invested in over 70 companies, which collectively have attracted more than £1 billion in private investment, demonstrating the fund's catalytic role in attracting further capital into deep tech ventures. Furthermore, the fund boasts 15 successful exits, including four initial public offerings (IPOs), underscoring its ability to identify and nurture promising ventures from the laboratory to market success.

Investor Profile

UK Innovation & Science Seed Fund has backed more than 116 startups, with 9 new investments in the last 12 months alone. The firm has led 37 rounds, about 32% of its total and boasts 7 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Seed, Series Unknown, Series A rounds (top funding stages).
  • Majority of deals are located in United Kingdom, United States.
  • Strong thematic focus on Biotechnology, Health Care, Medical.
  • Led 1 rounds in the past year.
  • Typical check size: $312.5K – $1.3M.

Stage Focus

  • Seed (62%)
  • Series Unknown (21%)
  • Series A (6%)
  • Angel (3%)
  • Pre Seed (3%)
  • Grant (3%)
  • Series B (2%)
  • Series C (2%)

Country Focus

  • United Kingdom (99%)
  • United States (1%)

Industry Focus

  • Biotechnology
  • Health Care
  • Medical
  • Therapeutics
  • Life Science
  • Software
  • Manufacturing
  • Pharmaceutical
  • Medical Device
  • Electronics
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does UK Innovation & Science Seed Fund frequently co-invest with?

Longwall Venture
Europe, Oxfordshire, United Kingdom, Harwell
Co-Investments: 6
Innovate UK
Europe, Wiltshire, United Kingdom, Swindon
Co-Investments: 4
Wren Capital
Europe, England, United Kingdom, London
Co-Investments: 6
Oxford Technology Management
Europe, Oxfordshire, United Kingdom, Oxford
Co-Investments: 8
ACF Investors
Europe, Sheffield, United Kingdom, Sheffield
Co-Investments: 5
Midven
Europe, Birmingham, United Kingdom, Birmingham
Co-Investments: 5
Development Bank of Wales
Europe, Cardiff, United Kingdom, Cardiff
Co-Investments: 6
Future Planet Capital
Europe, England, United Kingdom, London
Co-Investments: 77
Scottish Enterprise
Europe, Glasgow City, United Kingdom, Glasgow
Co-Investments: 7
Parkwalk Advisors
Europe, England, United Kingdom, London
Co-Investments: 5

Which angels does UK Innovation & Science Seed Fund often collaborate with?

DD
Europe, Cambridgeshire, United Kingdom, Cambridge
Shared Deals: 1
MQ
Europe, Kingston upon Thames, United Kingdom
Shared Deals: 1
CS
Europe, England, United Kingdom, London
Shared Deals: 1
SH
Europe, Warwickshire, United Kingdom, Leamington Spa
Shared Deals: 1
DD
Europe, England, United Kingdom, London
Shared Deals: 1
EP
Europe, England, United Kingdom
Shared Deals: 1
OS
Europe, England, United Kingdom, London
Shared Deals: 1
Mark McCamish
North America, California, United States, Ventura
Shared Deals: 1
RY
Europe, England, United Kingdom, London
Shared Deals: 1
JM
North America, Massachusetts, United States, Cambridge
Shared Deals: 4

What are some of recent deals done by UK Innovation & Science Seed Fund?

Spaceflux

London, England, United Kingdom

Space Safety Services for a Sustainable Space Environment

Aerospace
SeedJul 24, 2025
Amount Raised: $7,332,394
Cryogenx

Hayes, Hillingdon, United Kingdom

Cryogenx manufactures and provides cryo suits that provide portable body cooling for heat stroke.

Health CareManufacturingMedicalMedical Device
SeedJul 15, 2025
Amount Raised: $2,219,847
Sention Technologies

London, England, United Kingdom

Sention Technologies is a battery cell intelligence firm that uses advanced diagnostic techniques and machine learning.

BatteryMachine LearningManufacturing
SeedMay 21, 2025
Amount Raised: $4,968,284
iFast Diagnostics

Northampton, Northamptonshire, United Kingdom

iFAST is addressing the Antimicrobial Susceptibility Testing market, reducing the spread of antimicrobial resistance.

Health Care
SeedNov 4, 2024
Amount Raised: $6,477,154
Ikarovec

Cambridge, Cambridgeshire, United Kingdom

Ikarovek is working on early stage assets intended for the treatment of diabetic macular edama.

BiotechnologyHealth CareLife Science
SeedOct 23, 2024
Amount Raised: $10,333,234
Antiverse

Cardiff, Cardiff, United Kingdom

Antiverse is dedicated to engineering the future of drug development to change the course of people's lives.

Artificial Intelligence (AI)BiotechnologyHealth CareLife ScienceMachine Learning
SeedOct 15, 2024
Amount Raised: $4,572,707
Lineat Composites

Bristol, Bristol, City of, United Kingdom

Lineat uses reclaimed carbon fiber to produce a fiber aligned tape that can be used to manufacture new composite components.

Advanced MaterialsManufacturingRenewable EnergySemiconductor
SeedOct 15, 2024
Amount Raised: $1,829,083
Aquark Technologies

Southampton, Southampton, United Kingdom

Aquark Technologies develops atom system to develop quantum applications, including atomic clocks, sensors, and navigation systems.

ManufacturingProduct DesignProduct Research
SeedSep 19, 2024
Amount Raised: $5,579,734
Solasta Bio

Glasgow, Glasgow City, United Kingdom

Solasta Bio develops environment-friendly products that meet a global need for new and effective crop protection.

Biotechnology
Series ASep 11, 2024
Amount Raised: $13,950,820
HonuWorx

Aberdeen, Aberdeen City, United Kingdom

HonuWorx is a technology firm offering autonomous systems that reduce costs and the environmental footprint of robotic system operation.

Autonomous VehiclesMarine TechnologyRoboticsSoftware
SeedSep 9, 2024