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Unorthodox Ventures

North America, Texas, United States, Austin

Description

Unorthodox Ventures, based in Austin, Texas, distinguishes itself from traditional venture capital firms by operating as a "venture operating company." Co-founded in 2019 by the legendary entrepreneur John Paul DeJoria, known for co-founding Paul Mitchell and Patrón Tequila, and his son Scott DeJoria, the firm brings a wealth of hands-on operational experience to its portfolio companies. Their unique approach emphasizes deep, long-term partnerships, focusing on helping small to medium-sized businesses (SMBs) and disruptive startups build enduring and endearing brands. They are not merely capital providers but active partners committed to fostering growth and market presence.

The firm's investment philosophy centers on investing in people and proven concepts rather than just business plans. They seek out companies with strong leadership, a demonstrated product or service, and significant growth potential. Unorthodox Ventures is particularly interested in businesses that can benefit from their extensive expertise in branding, marketing, distribution, and operational scaling. This hands-on involvement is a cornerstone of their strategy, aiming to transform promising ventures into market leaders through strategic guidance and direct support.

Unorthodox Ventures typically provides initial investments ranging from $1 million to $10 million, positioning them to support a wide array of early-stage to growth-stage companies. Beyond capital, their value proposition includes direct access to a network of seasoned professionals and the strategic acumen derived from building multi-billion dollar brands. They are committed to cultivating long-term relationships, working closely with founders to navigate challenges and capitalize on opportunities, ensuring their portfolio companies not only survive but thrive and establish a lasting market presence.

Investor Profile

Unorthodox Ventures has backed more than 21 startups, with 4 new investments in the last 12 months alone. The firm has led 8 rounds, about 38% of its total and boasts 0 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series Unknown, Series B, Series A rounds (top funding stages).
  • Majority of deals are located in United States, Israel, Switzerland.
  • Strong thematic focus on Health Care, Medical Device, Medical.
  • Typical check size: $1M – $10M.

Stage Focus

  • Series Unknown (29%)
  • Series B (24%)
  • Series A (19%)
  • Series C (10%)
  • Series E (10%)
  • Series D (5%)
  • Seed (5%)

Country Focus

  • United States (52%)
  • Israel (14%)
  • Switzerland (14%)
  • Germany (10%)
  • France (5%)
  • The Netherlands (5%)

Industry Focus

  • Health Care
  • Medical Device
  • Medical
  • Biotechnology
  • Fitness
  • Wellness
  • Construction
  • Information Technology
  • Food And Beverage
  • Apps
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Unorthodox Ventures frequently co-invest with?

Shifamed
North America, California, United States, Campbell
Co-Investments: 2
415 Capital
Europe, Bayern, Germany, Munich
Co-Investments: 3
CA
North America, Massachusetts, United States, Boston
Co-Investments: 4
The Capital Partnership
Europe, England, United Kingdom, London
Co-Investments: 4
Dreamit Ventures
North America, Pennsylvania, United States, Philadelphia
Co-Investments: 1
RV
North America, Maryland, United States, Baltimore
Co-Investments: 2
HealthTech Capital
North America, California, United States, Los Altos Hills
Co-Investments: 1
PM
Europe, Zurich, Switzerland, Pfaffikon
Co-Investments: 4
Alliance of Angels
North America, Washington, United States, Seattle
Co-Investments: 1
AV
North America, California, United States, San Francisco
Co-Investments: 4

Which angels does Unorthodox Ventures often collaborate with?

CS
North America, Texas, United States, Austin
Shared Deals: 1

What are some of recent deals done by Unorthodox Ventures?

Supira Medical

Los Gatos, California, United States

Supira Medical is a clinical-stage company that develops catheter-based circulatory support devices for patients with heart conditions.

Health CareMedicalMedical Device
Series EMar 26, 2025
Amount Raised: $120,000,000
Laplace Interventional

Plymouth, Minnesota, United States

Laplace is a medical device company that develops transcatheter tricuspid valve technology.

Health CareMedicalMedical Device
Series CMar 16, 2025
Amount Raised: $22,000,000
Sonavex

Baltimore, Maryland, United States

Sonavex is a developer of an imaging technology designed to visualize and quantify critical data to detect anastomotic blood clots.

BiotechnologyHealth CareMedical
Series AOct 24, 2024
Amount Raised: $15,000,000
CorFlow Therapeutics

Baar, Zug, Switzerland

CorFlow Therapeutics is a medtech startup that develops proprietary technologies for diagnosis and treatment of microvascular obstructions.

BiotechnologyManufacturingMedicalMedical Device
Series BSep 10, 2024
Amount Raised: $48,489,444
Adona Medical

Los Gatos, California, United States

Adona Medical is a technology-based company that designs and develops heart failure management systems to improve heart care.

Health CareMedicalMedical Device
Series CJul 10, 2024
Amount Raised: $33,500,000
FIRMUS

Herzliya, Tel Aviv, Israel

FIRMUS helps construction companies identify and mitigate design risks in all phases of construction projects

ConstructionInformation ServicesInformation Technology
Series UnknownMay 15, 2024
ConKay Medical Systems

Pleasanton, California, United States

ConKay Medical Systems is an early-stage medical device company advancing solutions to treat valvular regurgitation in patients.

Health Care
SeedMar 18, 2024
Amount Raised: $1,800,000
Laza Medical

Pfaffikon, Zurich, Switzerland

Laza Medical is a startup focused on producing a high-quality AI-powered robotic imaging solution for cardiovascular treatments.

HospitalMedicalMedical DeviceWellness
Series ADec 12, 2023
Amount Raised: $36,000,000
CarThera

Paris, Ile-de-France, France

CarThera designs and develops innovative therapeutic ultrasound-based medical devices for treating brain disorders.

BiotechnologyHealth CareMedical DeviceTherapeutics
Series BDec 11, 2023
Amount Raised: $4,844,414
Corporis Medical

Maastricht, Limburg, The Netherlands

Corporis Medical is a developer and commercialiser of innovative medical devices.

CommercialMedicalMedical Device
Series BDec 7, 2023
Amount Raised: $4,315,921