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Ysios Capital

Europe, Pais Vasco, Spain, San Sebastian

Description

Ysios Capital is a prominent European venture capital firm headquartered in San Sebastian, Spain, with a dedicated focus on the life sciences sector. Established as a leading investor, the firm primarily targets highly innovative companies globally, specializing in areas such as therapeutics, medical devices, and diagnostics. Their investment philosophy centers on identifying and nurturing groundbreaking scientific advancements that address significant unmet medical needs, aiming to translate cutting-edge research into tangible healthcare solutions.

The firm employs a comprehensive investment strategy, typically engaging with companies from early-stage development through to growth stages. Ysios Capital is known for its hands-on approach, providing not only capital but also strategic guidance, operational support, and access to a broad network of industry experts. This collaborative model is designed to accelerate the development and commercialization of their portfolio companies' technologies, ensuring they are well-positioned for success in the competitive global life sciences market.

Ysios Capital has successfully raised multiple funds, demonstrating a strong track record and investor confidence. Their latest fund, Ysios BioFund III, closed in 2023 with a substantial €194 million, significantly bolstering their capacity to invest in promising life science ventures. Across all its funds, Ysios Capital manages assets exceeding €380 million, solidifying its position as a major player in the European biotech investment landscape. The firm's initial investments typically range from €3 million to €10 million, with the potential for follow-on investments that can bring the total commitment per company up to €20 million over the investment lifecycle. This flexible investment approach allows them to support companies through various critical development milestones.

Investor Profile

Ysios Capital has backed more than 75 startups, with 4 new investments in the last 12 months alone. The firm has led 24 rounds, about 32% of its total and boasts 13 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series A, Series B, Series C rounds (top funding stages).
  • Majority of deals are located in Spain, United States, The Netherlands.
  • Strong thematic focus on Biotechnology, Health Care, Medical.
  • Typical check size: $3.2M – $10.8M.

Stage Focus

  • Series A (28%)
  • Series B (28%)
  • Series C (17%)
  • Series Unknown (11%)
  • Series D (7%)
  • Series F (4%)
  • Series E (3%)
  • Series G (1%)
  • Post Ipo Equity (1%)

Country Focus

  • Spain (33%)
  • United States (19%)
  • The Netherlands (16%)
  • Switzerland (11%)
  • Denmark (9%)
  • France (7%)
  • Sweden (3%)
  • United Kingdom (1%)
  • Belgium (1%)

Industry Focus

  • Biotechnology
  • Health Care
  • Medical
  • Pharmaceutical
  • Therapeutics
  • Medical Device
  • Health Diagnostics
  • Life Science
  • Biopharma
  • Hospital
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Ysios Capital frequently co-invest with?

Criteria Venture Tech
Europe, Catalonia, Spain, Barcelona
Co-Investments: 12
Forbion Capital Partners
Europe, Noord-Holland, The Netherlands, Naarden
Co-Investments: 10
Andera Partners
Europe, Ile-de-France, France, Paris
Co-Investments: 9
Novo Holdings
Europe, Hovedstaden, Denmark, Hellerup
Co-Investments: 8
Kurma Partners
Europe, Ile-de-France, France, Paris
Co-Investments: 13
HealthCap
Europe, Stockholms Lan, Sweden, Stockholm
Co-Investments: 8
EQT Life Sciences
Europe, Noord-Holland, The Netherlands, Amsterdam
Co-Investments: 12
Idinvest Partners
Europe, Ile-de-France, France, Paris
Co-Investments: 8
Roche Venture Fund
Europe, Basel-Stadt, Switzerland, Basel
Co-Investments: 7
Gilde Healthcare
Europe, Utrecht, The Netherlands, Utrecht
Co-Investments: 15

Which angels does Ysios Capital often collaborate with?

HT
Europe, Noord-Brabant, The Netherlands, Tilburg
Shared Deals: 1

What are some of recent deals done by Ysios Capital?

Splice Bio

Barcelona, Catalonia, Spain

Splice Bio develops gene therapies using its Protein Splicing platform for genetic diseases.

BiotechnologyLife ScienceMedicalPharmaceutical
Series BJun 11, 2025
Amount Raised: $135,000,000
ReproNovo

Lausanne, Vaud, Switzerland

ReproNovo specializes in reproductive health and women's health.

BiotechnologyFertilityHealth CareLife Science
Series AMay 21, 2025
Amount Raised: $65,000,000
Neurona Therapeutics

San Francisco, California, United States

Neurona Therapeutics develops cell therapies for neurological disorders, focusing on treatments like NRTX-1001 for epilepsy.

BiotechnologyHealth CareTherapeutics
Series FApr 3, 2025
Amount Raised: $102,000,000
ADCendo

Copenhagen, Hovedstaden, Denmark

ADCendo ApS is a biotech company dedicated to developing new types of anti-cancer drugs.

BiotechnologyHealth Care
Series BNov 25, 2024
Amount Raised: $135,000,000
ADCendo

Copenhagen, Hovedstaden, Denmark

ADCendo ApS is a biotech company dedicated to developing new types of anti-cancer drugs.

BiotechnologyHealth Care
Series AMay 29, 2024
Amount Raised: $17,281,921
Memo Therapeutics

Schlieren, Zurich, Switzerland

Memo Therapeutics is an innovator in the field of antibody discovery and immune repertoire analysis.

BiotechnologyCollaboration
Series CMay 7, 2024
Amount Raised: $22,015,012
Engrail Therapeutics

San Diego, California, United States

Engrail Therapeutics is a developer of medicines to transform the lives of patients with life-limiting diseases of the nervous system.

Health CareLife ScienceMedicalPharmaceutical
Series BMar 19, 2024
Amount Raised: $157,000,000
Neurona Therapeutics

San Francisco, California, United States

Neurona Therapeutics develops cell therapies for neurological disorders, focusing on treatments like NRTX-1001 for epilepsy.

BiotechnologyHealth CareTherapeutics
Series EFeb 8, 2024
Amount Raised: $120,000,000
Kynexis

Naarden, Noord-Holland, The Netherlands

Kynexis is advancing the first potential precision medicine for the treatment of cognitive impairment associated with schizophrenia (CIAS).

BiotechnologyHealth CareMedicalTherapeutics
Series ANov 7, 2023
Amount Raised: $60,970,914
Xeltis

Eindhoven, Noord-Brabant, The Netherlands

Xeltis is a clinical-stage medtech company with the world’s most advanced polymer-based platform of restorative cardiovascular devices.

Health CareMedical DeviceTherapeutics
Series DAug 14, 2023
Amount Raised: $13,634,767