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Ally Bridge Group

Asia, Hong Kong Island, Hong Kong, Hong Kong

Description

Ally Bridge Group is a prominent global healthcare-focused investment firm, established by Frank Yu. Headquartered in Hong Kong with additional offices in New York and Beijing, the firm employs a multi-strategy approach, encompassing venture capital, growth equity, leveraged buyouts, and public equity investments. This broad mandate allows Ally Bridge Group to invest across the entire healthcare ecosystem, from innovative early-stage companies to established public enterprises. A key differentiator for the firm is its strong emphasis on cross-border opportunities, particularly facilitating the growth and expansion of healthcare innovations between the US and China markets.

The firm's investment philosophy centers on identifying and supporting companies with disruptive technologies and strong growth potential within the biotechnology, pharmaceuticals, medical devices, diagnostics, and healthcare services sectors. Ally Bridge Group is known for making substantial commitments, often leading or co-leading significant funding rounds for its portfolio companies. For instance, the firm was a key investor in Insilico Medicine's $255 million Series C round in 2021, demonstrating their capacity to deploy considerable capital into promising ventures. Their portfolio includes notable companies such as GRAIL (acquired by Illumina), WuXi AppTec, and Zai Lab, reflecting their focus on high-impact healthcare innovators.

Ally Bridge Group manages a substantial amount of capital, with reports indicating over $2 billion in assets under management. Since its inception, the firm has invested over $2 billion across various healthcare companies globally, underscoring its significant presence and influence in the sector. Their typical first check sizes reflect their focus on growth-stage and buyout opportunities. While specific figures can vary based on the investment stage and deal structure, their initial commitments generally range from approximately $20 million for significant growth equity rounds to upwards of $150 million for larger growth or strategic buyout transactions, positioning them as a major financial partner for scaling healthcare enterprises.

Investor Profile

Ally Bridge Group has backed more than 92 startups, with 13 new investments in the last 12 months alone. The firm has led 37 rounds, about 40% of its total and boasts 43 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Post Ipo Equity, Series D, Series B rounds (top funding stages).
  • Majority of deals are located in United States, China, Canada.
  • Strong thematic focus on Biotechnology, Health Care, Medical.
  • Led 9 rounds in the past year.
  • Typical check size: $20M – $150M.

Stage Focus

  • Post Ipo Equity (23%)
  • Series D (14%)
  • Series B (14%)
  • Series C (13%)
  • Series Unknown (10%)
  • Private Equity (8%)
  • Series E (7%)
  • Series A (5%)
  • Series G (2%)
  • Series F (2%)

Country Focus

  • United States (82%)
  • China (7%)
  • Canada (4%)
  • Ireland (2%)
  • United Kingdom (2%)
  • Singapore (1%)
  • Israel (1%)
  • France (1%)

Industry Focus

  • Biotechnology
  • Health Care
  • Medical
  • Therapeutics
  • Medical Device
  • Pharmaceutical
  • Life Science
  • Biopharma
  • Oncology
  • Health Diagnostics
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Ally Bridge Group frequently co-invest with?

OrbiMed
North America, New York, United States, New York
Co-Investments: 16
Surveyor Capital
North America, Illinois, United States, Chicago
Co-Investments: 9
Avidity Partners
North America, Texas, United States, Dallas
Co-Investments: 9
T. Rowe Price
North America, Maryland, United States, Baltimore
Co-Investments: 13
Bain Capital Life Sciences
North America, Massachusetts, United States, Boston
Co-Investments: 8
RA Capital Management
North America, Massachusetts, United States, Boston
Co-Investments: 13
Rock Springs Capital
North America, Maryland, United States, Baltimore
Co-Investments: 11
Perceptive Advisors
North America, New York, United States, New York
Co-Investments: 16
Venrock
North America, California, United States, Palo Alto
Co-Investments: 9
Janus Henderson Investors
Europe, England, United Kingdom, London
Co-Investments: 12

Which angels does Ally Bridge Group often collaborate with?

Daphne Teo
Asia, Singapore
Shared Deals: 1
SH
North America, California, United States, Santa Monica
Shared Deals: 1

What are some of recent deals done by Ally Bridge Group?

atai Life Sciences

Munich, Bayern, Germany

Atai Life Sciences develops innovative mental health treatments that address significant unmet medical needs.

BiotechnologyLife ScienceMental HealthNeuroscienceTherapeutics
Post Ipo EquityJul 1, 2025
Amount Raised: $50,000,000
LEXEO Therapeutics

New York, New York, United States

LEXEO Therapeutics utilizes gene therapy to treat genetically defined cardiovascular and central nervous system diseases.

BiotechnologyLife ScienceTherapeutics
Post Ipo EquityMay 27, 2025
Amount Raised: $80,000,000
Kandu Health

Campbell, California, United States

Kandu Health is a tech-enabled healthcare company that provides stroke recovery training, stroke detection research, and education services.

EducationHealth CareMedicalOnline PortalsTraining
Series UnknownApr 8, 2025
Amount Raised: $30,000,000
Epicrispr Biotechnologies

South San Francisco, California, United States

Epic Bio's strength is a relentless focus on ushering in a new era of gene regulation.

BiotechnologyHealth Care
Series BMar 26, 2025
Amount Raised: $68,000,000
Cardiac Dimensions

Kirkland, Washington, United States

Cardiac Dimensions is a medical device company developing tools and techniques for the treatment of heart failure and related conditions.

BiotechnologyHealth CareMedical Device
Series EMar 20, 2025
Amount Raised: $53,000,000
Arbor Biotechnologies

Cambridge, Massachusetts, United States

Arbor Biotechnologies is a biotechnology company specializing in next-generation gene editing therapeutics to treat genetic diseases.

BiopharmaBiotechnologyLife Science
Series CMar 18, 2025
Amount Raised: $73,900,000
Aadi Bioscience

Pacific Palisades, California, United States

Aadi Bioscience develops a potentially mTOR inhibitor for targeted patient populations in oncology and cardiovascular diseases.

BiopharmaBiotechnologyLife ScienceOncology
Post Ipo EquityMar 4, 2025
Amount Raised: $100,000,000
VitalConnect

San Jose, California, United States

VitalConnect offers wearable biosensor technology for wireless patient monitoring in both hospital and remote patient populations.

BiotechnologyHealth CareMedical DeviceWearables
Series UnknownFeb 19, 2025
Amount Raised: $100,000,000
Tectonic Therapeutic

Allston, Massachusetts, United States

Tectonic Therapeutic is a biotechnology company which focuses on scientific research in biochemistry and molecular pharmacology.

Biotechnology
Post Ipo EquityFeb 3, 2025
Amount Raised: $185,000,000
Aerin Medical

Mountain View, California, United States

Aerin Medical is a health technology company that develops therapeutic devices to improve nasal breathing.

BiotechnologyHealth CareMedical DeviceTherapeutics
Private EquityJan 13, 2025
Amount Raised: $32,500,000