Define Ventures

Define Ventures is a prominent early-stage venture capital firm based in San Francisco, California, exclusively focused on investing in digital health companies. Established in 2018, the firm has rapidly built a significant presence in the healthcare technology landscape, aiming to support innovative solutions that transform patient care and industry efficiency. Define Ventures partners with founders at the Seed and Series A stages, providing not only capital but also strategic guidance and operational support to help these nascent companies scale.

The firm has demonstrated substantial fundraising success, managing over $900 million in assets across its three funds. This includes its inaugural Fund I at $150 million, followed by Fund II at $300 million, and most recently, Fund III, which closed at $460 million in March 2023. This capital base enables Define Ventures to be a lead investor in many of its rounds. Their typical initial check sizes for new investments generally range from $5 million to $20 million, reflecting their commitment to providing meaningful early-stage capital.

Define Ventures' investment thesis centers on identifying companies that leverage technology to address critical challenges in healthcare, from improving access and affordability to enhancing clinical outcomes. Their portfolio includes over 60 companies, featuring notable names such as Hinge Health, Cohere Health, and Unite Us, all of which have made significant strides in their respective digital health sectors. The firm's deep specialization in digital health allows it to offer tailored expertise and a robust network to its portfolio companies, fostering their growth and market penetration within a complex and rapidly evolving industry.