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DeNovo Ventures

North America, California, United States, Saratoga

Description

DeNovo Ventures is a specialized venture capital firm established in 2000, focusing exclusively on the medical device sector. Based in Saratoga, California, the firm was founded by a team of seasoned investors and experienced medical device entrepreneurs who sought to leverage their deep industry knowledge and operational expertise to identify and nurture innovative healthcare technologies. Their investment strategy is centered on early to growth-stage companies developing novel medical devices that address significant unmet clinical needs and have the potential for substantial market impact.

The firm is known for its hands-on approach, often providing strategic guidance, operational support, and access to their extensive network within the medical device industry. DeNovo Ventures has raised significant capital over its history, with its third fund, DeNovo Ventures III, L.P., closing at $250 million. This substantial capital base allows them to support portfolio companies through various stages of development, from product conceptualization and regulatory approval to commercialization and market expansion. They typically look for companies with strong intellectual property, clear clinical utility, and experienced management teams.

DeNovo Ventures has historically deployed capital across a diverse range of medical device sub-sectors, including cardiovascular, orthopedics, neurostimulation, and surgical tools. Their investment philosophy emphasizes long-term partnerships, aiming to build enduring value by helping companies navigate the complex landscape of medical device development and commercialization. With a total capital under management approaching $600 million across its three dedicated funds, the firm has established itself as a prominent and specialized investor in the highly regulated and capital-intensive medical device industry, contributing to the advancement of patient care through technological innovation.

Investor Profile

DeNovo Ventures has backed more than 86 startups, with 0 new investments in the last 12 months alone. The firm has led 11 rounds, about 13% of its total and boasts 24 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series B, Series C, Series D rounds (top funding stages).
  • Majority of deals are located in United States.
  • Strong thematic focus on Health Care, Medical Device, Biotechnology.
  • Typical check size: $3M – $10M.

Stage Focus

  • Series B (23%)
  • Series C (19%)
  • Series D (15%)
  • Series Unknown (15%)
  • Series A (8%)
  • Series E (7%)
  • Series F (5%)
  • Private Equity (3%)
  • Debt Financing (2%)
  • Post Ipo Equity (1%)

Country Focus

  • United States (100%)

Industry Focus

  • Health Care
  • Medical Device
  • Biotechnology
  • Medical
  • Health Diagnostics
  • Therapeutics
  • Pharmaceutical
  • Manufacturing
  • Biopharma
  • Beauty
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does DeNovo Ventures frequently co-invest with?

Accuitive Medical Ventures
North America, Georgia, United States, Duluth
Co-Investments: 8
SV Health Investors
North America, Massachusetts, United States, Boston
Co-Investments: 8
InterWest Partners
North America, California, United States, Menlo Park
Co-Investments: 8
Versant Ventures
North America, California, United States, Menlo Park
Co-Investments: 8
Johnson & Johnson Development Corporation
North America, New Jersey, United States, New Brunswick
Co-Investments: 10
Chicago Growth Partners
North America, Illinois, United States, Chicago
Co-Investments: 7
Delphi Ventures
North America, California, United States, San Mateo
Co-Investments: 15
Morgenthaler Ventures
North America, California, United States, Menlo Park
Co-Investments: 7
Advanced Technology Ventures
North America, California, United States, Menlo Park
Co-Investments: 7
Latterell Venture Partners
North America, California, United States, San Francisco
Co-Investments: 12

What are some of recent deals done by DeNovo Ventures?

Milo

San Francisco, California, United States

Milo is a group action communicator, sophisticated wireless networking, audio processing & powerful hardware in a carefully crafted design.

AudioCommunication HardwareConsumer ElectronicsInformation Technology
Series AJan 8, 2023
Amount Raised: $12,000,000
Avedro

Waltham, Massachusetts, United States

Avedro is a medical device and pharmaceutical company advancing the science and technology of corneal cross-linking.

Health CareMedical DevicePharmaceutical
Series FMay 2, 2018
Amount Raised: $25,000,000
Avedro

Waltham, Massachusetts, United States

Avedro is a medical device and pharmaceutical company advancing the science and technology of corneal cross-linking.

Health CareMedical DevicePharmaceutical
Series UnknownApr 27, 2017
Amount Raised: $42,000,000
TearScience

Morrisville, North Carolina, United States

TearScience develops devices that provide significant clinical identification and treatment of evaporative dry eye.

BiotechnologyClinical TrialsHealth CareMedicalMedical Device
Series DApr 14, 2016
Amount Raised: $19,225,391
Benvenue Medical

Santa Clara, California, United States

Benvenue Medical is a biotech company developing innovative and minimally invasive surgical solutions for the treatment of spinal disorders.

BiotechnologyHealth CareMedicalMedical Device
Series FJan 7, 2016
Amount Raised: $23,000,000
Benvenue Medical

Santa Clara, California, United States

Benvenue Medical is a biotech company developing innovative and minimally invasive surgical solutions for the treatment of spinal disorders.

BiotechnologyHealth CareMedicalMedical Device
Series EJun 18, 2014
Amount Raised: $40,000,000
Spinal Kinetics

Sunnyvale, California, United States

Spinal Kinetics partners with spine surgeons to develop motion preservation systems for the treatment of degenerative spine diseases.

Health CareMedical Device
Series UnknownJun 4, 2014
Amount Raised: $34,000,000
EndoGastric Solutions

San Mateo, California, United States

EGS manufactures EsophyX technology is used to reconstruct the gastroesophageal valve in the TIF 2.0 procedure.

Health CareHealth DiagnosticsMedical Device
Series GMay 6, 2014
Amount Raised: $30,000,000
MyoScience

Redwood City, California, United States

MyoScience develops and commercializes technology-driven dermatological products.

BiotechnologyPharmaceuticalTherapeutics
Series ESep 12, 2013
Amount Raised: $25,000,000
TRIA Beauty

Pleasanton, California, United States

TRIA Beauty develops and markets light-based therapeutic beauty systems for the consumer market.

BeautyCosmeticsE-Commerce
Private EquityJul 9, 2013
Amount Raised: $45,500,000