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SV Health Investors

North America, Massachusetts, United States, Boston

Description

SV Health Investors is a distinguished venture capital firm with a specialized focus on the biotechnology and broader healthcare industries. Headquartered in Boston, with additional operations in London, the firm boasts a comprehensive team of investment professionals and advisors deeply entrenched in life sciences and healthcare. With a history spanning over 29 years, SV Health Investors has cultivated a reputation for strategic investments across various stages of company development.

The firm employs a multi-strategy approach, managing funds across four distinct areas: Venture, Growth, Biotech Crossover, and the specialized Dementia Discovery Fund. Their Venture funds are primarily dedicated to early-stage biotechnology and medical device companies, seeking to foster innovation from its nascent stages. In contrast, their Growth funds target later-stage opportunities within healthcare services and digital health, supporting companies poised for significant expansion. This diversified strategy allows SV Health Investors to engage with a wide spectrum of healthcare innovation, from groundbreaking scientific discoveries to established service providers.

SV Health Investors has demonstrated substantial financial capacity and a strong track record. The firm has successfully raised 10 funds, accumulating over $3.0 billion in committed capital, underscoring its significant presence and resources within the healthcare investment landscape. Their strategic investments have led to impressive outcomes, including over 20 successful IPOs and more than 30 M&A transactions, showcasing their ability to identify and nurture companies towards successful exits. Typical initial investment sizes can vary significantly depending on the fund strategy, ranging from approximately $5 million for early-stage venture deals to upwards of $50 million for growth equity opportunities, reflecting their flexible and stage-appropriate investment philosophy.

Investor Profile

SV Health Investors has backed more than 320 startups, with 11 new investments in the last 12 months alone. The firm has led 75 rounds, about 23% of its total and boasts 91 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series A, Series B, Series Unknown rounds (top funding stages).
  • Majority of deals are located in United States, United Kingdom, Switzerland.
  • Strong thematic focus on Health Care, Biotechnology, Medical Device.
  • Led 3 rounds in the past year.
  • Typical check size: $5M – $50M.

Stage Focus

  • Series A (25%)
  • Series B (21%)
  • Series Unknown (17%)
  • Series C (10%)
  • Seed (8%)
  • Series D (6%)
  • Debt Financing (6%)
  • Post Ipo Equity (3%)
  • Private Equity (3%)
  • Series E (2%)

Country Focus

  • United States (79%)
  • United Kingdom (14%)
  • Switzerland (2%)
  • Austria (2%)
  • Australia (1%)
  • Germany (1%)
  • Ireland (1%)

Industry Focus

  • Health Care
  • Biotechnology
  • Medical Device
  • Medical
  • Therapeutics
  • Pharmaceutical
  • Biopharma
  • Life Science
  • Health Diagnostics
  • Information Technology
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does SV Health Investors frequently co-invest with?

OrbiMed
North America, New York, United States, New York
Co-Investments: 15
Accuitive Medical Ventures
North America, Georgia, United States, Duluth
Co-Investments: 21
The Carlyle Group
North America, District of Columbia, United States, Washington
Co-Investments: 15
New Leaf Venture Partners
North America, New York, United States, New York
Co-Investments: 11
Versant Ventures
North America, California, United States, Menlo Park
Co-Investments: 23
Atlas Venture
North America, Massachusetts, United States, Cambridge
Co-Investments: 13
Novo Holdings
Europe, Hovedstaden, Denmark, Hellerup
Co-Investments: 13
SR One
North America, Massachusetts, United States, Cambridge
Co-Investments: 12
Polaris Partners
North America, Massachusetts, United States, Boston
Co-Investments: 16
Clarus Ventures
North America, Massachusetts, United States, Cambridge
Co-Investments: 11

Which angels does SV Health Investors often collaborate with?

SH
North America, North Carolina, United States, Raleigh
Shared Deals: 1
TB
North America, Missouri, United States, St Louis
Shared Deals: 1
BG
North America, Washington, United States, Seattle
Shared Deals: 1
RS
North America, Colorado, United States, Denver
Shared Deals: 1
JF
North America, California, United States
Shared Deals: 1
JT
North America, Florida, United States, West Palm Beach
Shared Deals: 1
TF
North America, California, United States, San Jose
Shared Deals: 1

What are some of recent deals done by SV Health Investors?

Draig Therapeutics

Cardiff, New South Wales, Australia

Draig Therapeutics is a clinical-stage biopharmaceutical startup.

BiotechnologyTherapeutics
Series AJun 18, 2025
Amount Raised: $140,000,000
Therini Bio

San Francisco, California, United States

Therini Bio specializes in fibrin-targeting therapies to treat inflammatory neurological and retinal diseases.

BiotechnologyHealth CareMedicalTherapeutics
Series AMay 14, 2025
Amount Raised: $39,000,000
Imbria Pharmaceuticals

Boston, Massachusetts, United States

Imbria Pharmaceuticals is a clinical stage biotechnology company developing novel therapies for cardiometabolic diseases.

BiotechnologyHealth CareLife SciencePharmaceutical
Series BApr 10, 2025
Amount Raised: $59,195,818
Perfuze

Newcastle, Galway, Ireland

Perfuze is a medical device company developing catheter-based aspiration technology to treat acute ischemic stroke.

Health CareManufacturingMedicalMedical Device
Series UnknownMar 13, 2025
Amount Raised: $23,936,512
Ria Health

San Francisco, California, United States

Ria Health is an online platform providing telehealth services for alcohol use disorder.

Health CareMedicalmHealth
Series BFeb 25, 2025
Amount Raised: $6,500,000
AdvanCell

Sydney, New South Wales, Australia

AdvanCell is a clinical-stage radiopharmaceutical company that develops novel cancer therapeutics.

BiotechnologyClinical TrialsOncologyPharmaceutical
Series CFeb 3, 2025
Amount Raised: $112,000,000
TRex Bio

South San Francisco, California, United States

TRex Bio is a biotechnology company that treats diseases like cancer, fibrotic by studying human tissues.

BioinformaticsBiopharmaBiotechnology
Series BNov 13, 2024
Amount Raised: $84,000,000
Enara Bio

London, England, United Kingdom

Ervaxx is illuminating the immune interface to develop new cancer therapies.

BiotechnologyHealth CareTherapeutics
Series BOct 3, 2024
Amount Raised: $32,500,000
Spectrawave

Waltham, Massachusetts, United States

Spectrawave is a medical device company that develops optical diagnostic and therapeutic devices.

BiotechnologyHealth CareHealth DiagnosticsMedicalMedical Device
Series BSep 11, 2024
Amount Raised: $50,000,000
CSA Medical

Lutherville Timonium, Maryland, United States

CSA Medical is a provider of innovative spray cryotherapy medical device solutions.

BiotechnologyHealth CareMedicalMedical Device
Series DSep 9, 2024
Amount Raised: $53,000,000