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Epidarex Capital

North America, Maryland, United States, Bethesda

Description

Epidarex Capital is a transatlantic venture capital firm specializing in early-stage, high-growth life science and health technology companies. With offices in Bethesda, Maryland, and Edinburgh, UK, the firm strategically targets what it identifies as under-ventured markets within both the United States and the United Kingdom. Their investment thesis centers on identifying and nurturing groundbreaking innovations emerging from leading research universities and spin-out companies. Epidarex aims to bridge the gap between scientific discovery and commercialization, focusing on novel therapeutics, medical devices, and digital health solutions that address significant unmet medical needs.

The firm's investment approach is hands-on, often taking a lead or co-lead position in financing rounds. They are committed to providing not only capital but also strategic guidance and operational support to their portfolio companies, leveraging their deep industry expertise and extensive network. Epidarex seeks to build robust companies with strong management teams and clear pathways to market, emphasizing long-term value creation. Their focus on early-stage opportunities means they are often the first institutional investor, playing a critical role in a company's foundational development.

Epidarex Capital has demonstrated significant fundraising success, having closed three dedicated funds to date. Their most recent fund, Epidarex Capital III, closed in 2021 with commitments totaling £103 million (approximately $140 million at the time). Across all three funds, Epidarex has raised over $300 million, underscoring their substantial capacity to invest in the life sciences sector. For initial investments, Epidarex typically deploys between $2 million and $10 million, with the flexibility to participate in subsequent follow-on rounds as their portfolio companies achieve key milestones and require further capital for growth and development. This strategic capital deployment allows them to support companies from their earliest stages through to significant clinical and commercial progress.

Investor Profile

Epidarex Capital has backed more than 47 startups, with 2 new investments in the last 12 months alone. The firm has led 22 rounds, about 47% of its total and boasts 3 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series A, Series B, Seed rounds (top funding stages).
  • Majority of deals are located in United Kingdom, United States, Germany.
  • Strong thematic focus on Biotechnology, Therapeutics, Health Care.
  • Typical check size: $2M – $10M.

Stage Focus

  • Series A (53%)
  • Series B (17%)
  • Seed (15%)
  • Series Unknown (9%)
  • Series E (2%)
  • Series C (2%)
  • Series D (2%)

Country Focus

  • United Kingdom (70%)
  • United States (21%)
  • Germany (9%)

Industry Focus

  • Biotechnology
  • Therapeutics
  • Health Care
  • Life Science
  • Medical
  • Health Diagnostics
  • Pharmaceutical
  • Oncology
  • Biopharma
  • Medical Device
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Epidarex Capital frequently co-invest with?

Boehringer Ingelheim Venture Fund
Europe, Rheinland-Pfalz, Germany, Ingelheim Am Rhein
Co-Investments: 3
Novartis Venture Fund
Europe, Basel-Stadt, Switzerland, Basel
Co-Investments: 4
Sante Ventures
North America, Texas, United States, Austin
Co-Investments: 3
British Patient Capital
Europe, Sheffield, United Kingdom, Sheffield
Co-Investments: 3
Scottish Investment Bank
Europe, Glasgow City, United Kingdom, Glasgow
Co-Investments: 6
F-Prime Capital
North America, Massachusetts, United States, Cambridge
Co-Investments: 3
Sofinnova Partners
Europe, Ile-de-France, France, Paris
Co-Investments: 4
M Ventures
Europe, Noord-Holland, The Netherlands, Amsterdam
Co-Investments: 3
Scottish Enterprise
Europe, Glasgow City, United Kingdom, Glasgow
Co-Investments: 4
Oxford Science Enterprises
Europe, Oxfordshire, United Kingdom, Oxford
Co-Investments: 3

Which angels does Epidarex Capital often collaborate with?

JT
Europe, Harjumaa, Estonia, Tallinn
Shared Deals: 1
DG
Europe, Cambridgeshire, United Kingdom, Cambridge
Shared Deals: 1

What are some of recent deals done by Epidarex Capital?

Harness Therapeutics

Cambridge, Cambridgeshire, United Kingdom

Harness Therapeutics is a developer of a platform for physiological upregulation of proteins using targeted translation enhancers, SINEUPs.

BiotechnologyLife Science
Series UnknownJan 27, 2025
Epsilogen

London, England, United Kingdom

Epsilogen is a developer of an immuno-oncology company intended to develop immunoglobulin antibodies to treat cancer.

BiopharmaBiotechnologyGeneticsLife ScienceOncologyTherapeutics
Series BSep 9, 2024
Amount Raised: $16,338,566
Theolytics

Oxford, Oxfordshire, United Kingdom

Theolytics is a clinical stage biotechnology company developing next-generation viral therapies.

BiotechnologyMedicalTherapeutics
Series UnknownApr 17, 2024
Amount Raised: $23,660,858
Curve Therapeutics

Southampton, Southampton, United Kingdom

Curve develops an innovative screening platform.

Biotechnology
Series AFeb 27, 2024
Amount Raised: $51,355,077
Enterprise Therapeutics

Falmer, East Sussex, United Kingdom

A UK-based developer of drugs to treat respiratory diseases

Health CareHealth DiagnosticsTherapeutics
Series BJan 29, 2024
Amount Raised: $33,056,380
Mironid

Newhouse, North Lanarkshire, United Kingdom

Mironid is a drug discovery company focused on therapeutics for degenerative kidney diseases, chronic inflammatory diseases, and cancer.

BiotechnologyHealth DiagnosticsLife ScienceTherapeutics
Series ASep 13, 2023
Amount Raised: $38,343,127
Theolytics

Oxford, Oxfordshire, United Kingdom

Theolytics is a clinical stage biotechnology company developing next-generation viral therapies.

BiotechnologyMedicalTherapeutics
Series AAug 25, 2023
Amount Raised: $27,797,378
Nyra Medical

Atlanta, Georgia, United States

Nyra Medical develops a catheter-plug technology to repair a leaky mitral valve in the heart.

Medical Device
Series ANov 18, 2022
Amount Raised: $20,000,000
RapidPulse

Miami, Florida, United States

RapidPulse is a privately held medical device company that develops minimally invasive vascular products for ischemic stroke

Health CareMedicalMedical Device
Series AAug 31, 2022
Amount Raised: $10,571,082
Harness Therapeutics

Cambridge, Cambridgeshire, United Kingdom

Harness Therapeutics is a developer of a platform for physiological upregulation of proteins using targeted translation enhancers, SINEUPs.

BiotechnologyLife Science
SeedMay 31, 2022
Amount Raised: $5,800,413