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Frazier Life Sciences

North America, California, United States, Menlo Park

Description

Frazier Life Sciences is the dedicated life sciences investment strategy of Frazier Healthcare Partners, a prominent private equity firm established in 1991. Based in Menlo Park, California, with an additional office in Seattle, Washington, the firm has a long-standing history of investing across the healthcare sector. Frazier Life Sciences specifically focuses on identifying, investing in, and building companies that are developing and commercializing novel therapeutics. Their investment philosophy often involves leading or co-leading financing rounds for early-stage and development-stage biopharmaceutical companies, providing significant capital and strategic guidance to help these ventures advance their pipelines.

The firm's commitment to the life sciences sector is underscored by its substantial capital raises. In 2022, Frazier Life Sciences successfully closed its eleventh fund, Frazier Life Sciences XI, with an impressive $830 million in committed capital. This followed the closure of Frazier Life Sciences X in 2019, which secured $675 million. These large fund sizes enable Frazier Life Sciences to make substantial initial investments and provide follow-on capital, supporting companies through various stages of clinical development and commercialization. Their portfolio typically comprises companies focused on a wide range of therapeutic areas, including oncology, immunology, rare diseases, and neuroscience.

Frazier Life Sciences is known for its hands-on approach, often working closely with management teams to build companies from inception or to scale existing businesses. Their typical first check sizes reflect their strategy of being a lead or significant investor in capital-intensive biopharmaceutical development. While specific initial check sizes can vary based on the stage and capital requirements of the company, Frazier Life Sciences generally commits between $15 million and $75 million for its initial investments. This substantial range allows them to back promising therapeutic platforms and drug candidates that require significant funding to reach key milestones, ultimately aiming to bring transformative medicines to patients.

Investor Profile

Frazier Life Sciences has backed more than 46 startups, with 14 new investments in the last 12 months alone. The firm has led 14 rounds, about 30% of its total and boasts 18 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Post Ipo Equity, Series B, Series A rounds (top funding stages).
  • Majority of deals are located in United States, United Kingdom, Canada.
  • Strong thematic focus on Biotechnology, Health Care, Therapeutics.
  • Led 5 rounds in the past year.
  • Typical check size: $15M – $75M.

Stage Focus

  • Post Ipo Equity (50%)
  • Series B (15%)
  • Series A (13%)
  • Series C (11%)
  • Series E (2%)
  • Series Unknown (2%)
  • Seed (2%)
  • Undisclosed (2%)
  • Series D (2%)

Country Focus

  • United States (76%)
  • United Kingdom (7%)
  • Canada (7%)
  • Sweden (4%)
  • Switzerland (2%)

Industry Focus

  • Biotechnology
  • Health Care
  • Therapeutics
  • Medical
  • Pharmaceutical
  • Biopharma
  • Life Science
  • Oncology
  • Product Research
  • Medical Device
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Frazier Life Sciences frequently co-invest with?

OrbiMed
North America, New York, United States, New York
Co-Investments: 7
Wellington Management
North America, Massachusetts, United States, Boston
Co-Investments: 7
Surveyor Capital
North America, Illinois, United States, Chicago
Co-Investments: 8
Venrock Healthcare Capital Partners
North America, California, United States, Palo Alto
Co-Investments: 8
Biotechnology Value Fund
North America, California, United States, San Francisco
Co-Investments: 7
TCG Crossover
North America, California, United States, Palo Alto
Co-Investments: 9
RA Capital Management
North America, Massachusetts, United States, Boston
Co-Investments: 9
Deep Track Capital
North America, Connecticut, United States, Greenwich
Co-Investments: 10
Logos Capital
North America, California, United States, San Francisco
Co-Investments: 12
Janus Henderson Investors
Europe, England, United Kingdom, London
Co-Investments: 10

What are some of recent deals done by Frazier Life Sciences?

Crescent Biopharma

Rockville, Maryland, United States

Crescent Biopharma is a biotechnology firm focused on developing novel precision-engineered medicines.

BiotechnologyHealth CareMedical Device
Post Ipo EquityJun 16, 2025
Amount Raised: $200,000,000
LEXEO Therapeutics

New York, New York, United States

LEXEO Therapeutics utilizes gene therapy to treat genetically defined cardiovascular and central nervous system diseases.

BiotechnologyLife ScienceTherapeutics
Post Ipo EquityMay 27, 2025
Amount Raised: $80,000,000
Jade Biosciences

Waltham, Massachusetts, United States

Jade Biosciences is developing transformative therapies to redefine the standard of care for inflammation and immunology indications.

Health CareTherapeutics
Post Ipo EquityApr 29, 2025
Amount Raised: $300,000,000
Attovia Therapeutics

San Carlos, California, United States

Attovia Therapeutics is a biologics platform specializing in biotherapeutics for immune-mediated diseases.

BiotechnologyHealth CareMedicalTherapeutics
Series CApr 15, 2025
Amount Raised: $90,000,000
Trevi Therapeutics

Sandy Hook, Connecticut, United States

Trevi Therapeutics is a clinical-stage biopharmaceutical company that develops drugs for treating uremic pruritus.

BiotechnologyHealth CarePharmaceutical
Post Ipo EquityDec 16, 2024
Amount Raised: $50,000,000
Palvella Therapeutics

Wayne, Pennsylvania, United States

Palvella Therapeutics focuses on relentlessly and selflessly serving abandoned patient populations with therapies.

BiotechnologyHealth CareLife ScienceTherapeutics
Post Ipo EquityDec 13, 2024
Maze Therapeutics

South San Francisco, California, United States

Maze Therapeutics is a biotechnology company that develops precision medicines for renal, cardiovascular, and metabolic diseases.

BiopharmaBiotechnologyGeneticsTherapeutics
Series DDec 3, 2024
Amount Raised: $115,000,000
35Pharma

Montreal, Quebec, Canada

35Pharma is a biopharmaceutical company that designs and develops innovative biologics for diseases of high unmet medical need.

BiopharmaBiotechnologyPharmaceutical
Series CNov 26, 2024
Amount Raised: $53,000,000

Crescent Biopharma is a biotechnology firm focused on developing novel precision-engineered medicines.

BiotechnologyHealth CareMedical Device
UndisclosedOct 29, 2024
Amount Raised: $200,000,000
Eledon Pharmaceuticals

Irvine, California, United States

Eledon Pharmaceuticals is a biotechnology company developing treatments for people undergoing organ or cellular transplantation.

BiotechnologyHealth CareMedicalPharmaceutical
Post Ipo EquityOct 29, 2024
Amount Raised: $85,000,000