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Hatteras Venture Partners

North America, North Carolina, United States, Durham

Description

Hatteras Venture Partners is a well-established venture capital firm headquartered in Durham, North Carolina, with a singular and deep focus on the life sciences sector. Since its inception in 2000, the firm has been a steadfast supporter of biomedical innovation, channeling capital into companies developing groundbreaking therapeutics, advanced medical devices, sophisticated diagnostics, and transformative digital health solutions. Their strategic location in the Research Triangle Park area positions them at the heart of a thriving biotech ecosystem, allowing them to closely engage with emerging scientific and entrepreneurial talent.

Over more than two decades, Hatteras Venture Partners has successfully raised and deployed significant capital across multiple funds. Their latest vehicle, Hatteras Venture Partners VII, closed in 2023 with $200 million in commitments, underscoring continued investor confidence in their specialized approach. This recent fund brings the firm's total capital under management to approximately $950 million across all seven funds. Hatteras typically targets early-stage companies, often taking a lead or co-lead position in Series A and Series B financing rounds, providing crucial initial capital for product development and clinical trials.

The firm's investment philosophy centers on identifying companies with strong intellectual property, compelling scientific foundations, and experienced management teams capable of navigating the complex regulatory and commercial landscapes of the life sciences. Their initial investment checks typically range from $3 million to $10 million, demonstrating their commitment to providing substantial early-stage funding necessary for capital-intensive biotech ventures. Beyond capital, Hatteras Venture Partners actively supports its portfolio companies with strategic guidance, industry connections, and operational expertise, aiming to accelerate their growth and maximize their potential for impactful innovation and successful exits.

Investor Profile

Hatteras Venture Partners has backed more than 119 startups, with 6 new investments in the last 12 months alone. The firm has led 44 rounds, about 37% of its total and boasts 25 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series A, Series B, Series Unknown rounds (top funding stages).
  • Majority of deals are located in United States, Canada.
  • Strong thematic focus on Biotechnology, Health Care, Medical.
  • Led 4 rounds in the past year.
  • Typical check size: $3M – $10M.

Stage Focus

  • Series A (39%)
  • Series B (24%)
  • Series Unknown (13%)
  • Series C (13%)
  • Seed (6%)
  • Series D (2%)
  • Private Equity (2%)
  • Series E (1%)
  • Convertible Note (1%)

Country Focus

  • United States (95%)
  • Canada (4%)

Industry Focus

  • Biotechnology
  • Health Care
  • Medical
  • Medical Device
  • Therapeutics
  • Pharmaceutical
  • Life Science
  • Health Diagnostics
  • Software
  • Clinical Trials
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Hatteras Venture Partners frequently co-invest with?

Mountain Group Capital
North America, Tennessee, United States, Nashville
Co-Investments: 12
Amgen Ventures
North America, California, United States, San Francisco
Co-Investments: 6
LabCorp
North America, North Carolina, United States, Burlington
Co-Investments: 6
Alexandria Venture Investments
North America, California, United States, Pasadena
Co-Investments: 14
Excelerate Health Ventures
North America, North Carolina, United States, Durham
Co-Investments: 8
New Enterprise Associates
North America, California, United States, Menlo Park
Co-Investments: 8
RA Capital Management
North America, Massachusetts, United States, Boston
Co-Investments: 8
OUP (Osage University Partners)
North America, Pennsylvania, United States, Bala Cynwyd
Co-Investments: 8
Lilly Ventures
North America, Indiana, United States, Indianapolis
Co-Investments: 5
Fletcher Spaght, Inc.
North America, Massachusetts, United States, Boston
Co-Investments: 7

Which angels does Hatteras Venture Partners often collaborate with?

RD
North America, North Carolina, United States, Raleigh
Shared Deals: 1
MB
North America, California, United States, San Francisco
Shared Deals: 1
IK
North America, California, United States
Shared Deals: 1
HJ
North America, New York, United States, New York
Shared Deals: 1
BJ
North America, North Carolina, United States, Raleigh
Shared Deals: 1
GM
North America, Texas, United States, Houston
Shared Deals: 1
MB
North America, North Carolina, United States, Durham
Shared Deals: 1
AP
North America, New Jersey, United States, Hackensack
Shared Deals: 1
BK
North America, California, United States, Los Angeles
Shared Deals: 1
TB
North America, New York, United States, New York
Shared Deals: 1

What are some of recent deals done by Hatteras Venture Partners?

GeneCentric Therapeutics

Durham, North Carolina, United States

GeneCentric Therapeutics develops and commercializes molecular diagnostic tests for oncologists and patients.

BiotechnologyHealth CareHealth Diagnostics
Series CJun 18, 2025
Amount Raised: $8,000,000
Atsena Therapeutics

Durham, North Carolina, United States

Atsena Therapeutics is a clinical-stage gene therapy company that develops novel treatments for inherited forms of blindness.

BiotechnologyHealth CareTherapeutics
Series CApr 2, 2025
Amount Raised: $150,000,000
410 Medical

Durham, North Carolina, United States

410 Medical is a medical device company dedicated to developing innovative products that enable frontline medical providers to improve care.

Health CareMedicalMedical Device
Series BMar 17, 2025
Amount Raised: $14,000,000
BEKHealth

Branford, Connecticut, United States

BEKhealth harnesses its AI-powered chart abstraction and patient-matching platform to optimize clinical research enrollment.

Clinical TrialsHospitalInformation ServicesMedicalMedical DevicePharmaceutical
Series UnknownFeb 13, 2025
Amount Raised: $4,000,000
Synaptrix

Alpharetta, Georgia, United States

Synaptrix is a healthcare company that offers medical products for postoperative pain treatment.

Health CareMedicalWellness
Series ANov 15, 2024
Amount Raised: $10,000,000
Axonis Therapeutics

Boston, Massachusetts, United States

Axonis Therapeutics is a neuro-focused biotechnology company that focuses on the development of novel neuromedicines.

BiotechnologyLife ScienceMedical
Series AOct 30, 2024
Amount Raised: $115,000,000
Endogenex

Plymouth, Minnesota, United States

Endogenex develops an endoscopic procedure to help patients with type 2 diabetes regain control of their blood glucose levels.

Health CareMedical DeviceTherapeutics
Series CJun 25, 2024
Amount Raised: $88,000,000
AtaCor Medical

San Clemente, California, United States

AtaCor Medical is a medical device maker.

Health CareMedical Device
Series CApr 24, 2024
Amount Raised: $28,000,000
iVEAcare

Minneapolis, Minnesota, United States

iVEAcare develops innovative neuromodulation therapy to treat unmet clinical needs.

Health CareMedical Device
Series AApr 22, 2024
Amount Raised: $27,500,000
Veralox Therapeutics

Frederick, Maryland, United States

Veralox Therapeutics develops small molecule therapeutics that treat the underlying pathologies of thrombosis and type one diabetes.

BiotechnologyMedicalPharmaceuticalTherapeutics
Series UnknownJun 20, 2023
Amount Raised: $24,000,000