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Inflection.xyz

North America, Massachusetts, United States, Boston

Description

Inflection.xyz is a Boston-based first-check venture capital firm established in 2022 by co-founders Aaron D. Jacobson and Matt F. Jacobson. The firm is dedicated to pioneering advancements in human-machine collaboration, focusing on the transformative potential at this intersection. Its investment thesis spans a range of innovative sectors, including artificial intelligence, robotics, the future of work, developer tools, and critical infrastructure. Inflection.xyz aims to identify and support early-stage companies that are building foundational technologies and applications designed to enhance human capabilities through intelligent systems.

The firm primarily targets pre-seed and seed-stage opportunities, positioning itself as a crucial early partner for nascent startups. Inflection.xyz raised its debut vehicle, Inflection.xyz Fund I, securing $10.5 million in capital to deploy across its target sectors. Typical first checks from Inflection.xyz range from $250,000 to $1 million, providing essential early funding to help founders validate their concepts and achieve initial traction. This strategic approach allows the firm to engage deeply with companies from their earliest stages, offering not just capital but also strategic guidance and network access.

By late 2022, Inflection.xyz had already demonstrated its active investment pace, building a portfolio of over 20 companies, including notable investments in firms like Anysphere (developer tools) and Dola (AI-powered event planning). The firm's initial fund attracted support from prominent venture capitalists, including Brad Feld of Foundry Group, Chris Dixon of Andreessen Horowitz, and Mike Volpi of Index Ventures, underscoring the confidence in Inflection.xyz's vision and leadership. This strong backing, combined with its specialized focus, positions Inflection.xyz as a significant early-stage investor in the evolving landscape of human-machine collaboration.

Investor Profile

Inflection.xyz has backed more than 38 startups, with 3 new investments in the last 12 months alone. The firm has led 7 rounds, about 18% of its total and boasts 0 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Seed, Pre Seed, Series Unknown rounds (top funding stages).
  • Majority of deals are located in United States, Germany, Switzerland.
  • Strong thematic focus on Blockchain, Cryptocurrency, Software.
  • Led 2 rounds in the past year.
  • Typical check size: $250K – $1M.

Stage Focus

  • Seed (47%)
  • Pre Seed (26%)
  • Series Unknown (16%)
  • Series A (8%)
  • Angel (3%)

Country Focus

  • United States (39%)
  • Germany (24%)
  • Switzerland (16%)
  • United Kingdom (8%)
  • Canada (3%)
  • Cayman Islands (3%)
  • Portugal (3%)

Industry Focus

  • Blockchain
  • Cryptocurrency
  • Software
  • Financial Services
  • Bitcoin
  • Fintech
  • Web3
  • Life Science
  • Information Technology
  • Decentralized Finance (Defi)
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Inflection.xyz frequently co-invest with?

BACKED VC
Europe, England, United Kingdom, London
Co-Investments: 3
Speedinvest
Europe, Wien, Austria, Vienna
Co-Investments: 3
BlueYard Capital
Europe, Berlin, Germany, Berlin
Co-Investments: 4
Protocol Labs
North America, California, United States, San Francisco
Co-Investments: 4
1kx
Europe, Berlin, Germany, Berlin
Co-Investments: 3
Placeholder
North America, New York, United States, New York
Co-Investments: 5
Compound
North America, New York, United States, New York
Co-Investments: 3
Fabric Ventures
Europe, England, United Kingdom, London
Co-Investments: 3
Cherry Ventures
Europe, Berlin, Germany, Berlin
Co-Investments: 2
The LAO
North America, New York, United States, Brooklyn
Co-Investments: 3

Which angels does Inflection.xyz often collaborate with?

Patricio Worthalter
South America, Buenos Aires, Argentina
Shared Deals: 2
Balaji Srinivasan
Asia, Central Region, Singapore, Singapore
Shared Deals: 7
David Choi
North America, United States
Shared Deals: 1
AT
North America, Massachusetts, United States, Boston
Shared Deals: 1
Kalos NFT
North America, Ontario, Canada, Toronto
Shared Deals: 2
Chen Magen
Asia, Israel
Shared Deals: 1
Andrew Keys
North America, Puerto Rico
Shared Deals: 2
NJ
North America, California, United States, San Francisco
Shared Deals: 2
MA
North America, California, United States, San Francisco
Shared Deals: 2
RM
North America, California, United States, San Francisco
Shared Deals: 2

What are some of recent deals done by Inflection.xyz?

Nordic Air Defence

Segeltorp, Stockholms Lan, Sweden

NAD maintains democratic values, which are essential to both societal stability and human advancement in a world that is changing quickly.

Pre SeedJul 3, 2025
Amount Raised: $3,000,000
Ubitium

Düsseldorf, Nordrhein-Westfalen, Germany

Ubiquitous computing, universal RISC-V microprocessor

Semiconductor
SeedNov 21, 2024
Amount Raised: $3,700,000
Fabric Cryptography

San Francisco, California, United States

Fabric is a verifiable processing unit startup that develops a custom cryptography hardware to accelerate cryptography algorithms.

ComputerNetwork HardwareQuantum ComputingWeb3
Series AAug 19, 2024
Amount Raised: $33,000,000
Lodestar

London, England, United Kingdom

Space Research Technology

3D PrintingSpace Travel
Pre SeedJul 25, 2024
Amount Raised: $2,495,773

Particle is a decentralized leverage trading system that allows any digital asset to be traded without permission.

BlockchainNon-Fungible Token (NFT)Trading Platform
SeedJan 12, 2024
Modulus

San Francisco, California, United States

Modulus uses cryptography to verify that AI results weren't doctored.

Artificial Intelligence (AI)
SeedNov 1, 2023
Amount Raised: $6,300,000
Tune Insight

Lausanne, Vaud, Switzerland

Tune Insight orchestrates secure collaborations on sensitive data between multiple organizations to extract collective insights.

Data IntegrationSoftware
SeedSep 28, 2023
Amount Raised: $3,400,000
Anytype

Berlin, Berlin, Germany

Anytype is a developer of file storage software for Web3 that is intended to provide a secure location for digital content.

BlockchainOperating SystemsSoftware
Series AAug 23, 2023
Amount Raised: $13,364,858
LabDAO

Berlin, Berlin, Germany

LabDAO is a research organization designed to unlock progress in the computational life sciences.

BiotechnologyLife ScienceProduct Research
SeedMay 23, 2023
Amount Raised: $3,600,000
Radical

Seattle, Washington, United States

Radical builds high-altitude solar aircraft to provide direct-to-handset LTE or 5G internet.

AerospaceInternetTelecommunications
Pre SeedApr 5, 2023
Amount Raised: $500,000