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Lifeforce Capital

North America, California, United States, San Francisco

Description

Lifeforce Capital is an early-stage venture capital firm based in San Francisco, California, dedicated to investing in transformative digital health companies. The firm primarily focuses on startups that are pioneering new care delivery models or enhancing the efficiency of therapeutic development. Their investment thesis centers on leveraging technology to address critical challenges within the healthcare ecosystem, aiming to improve patient outcomes, reduce costs, and expand access to care.

Lifeforce Capital actively seeks out innovative solutions across various segments of digital health, including virtual care platforms, AI-driven diagnostics and drug discovery, precision medicine, and patient engagement tools. They partner with visionary founders who are building scalable businesses designed to reshape how healthcare services are consumed and delivered, from prevention and diagnosis to treatment and ongoing management.

As an early-stage investor, Lifeforce Capital typically leads or co-leads Seed and Series A funding rounds. Their initial check size for investments generally ranges from $1 million to $5 million, providing substantial early capital to promising ventures. The firm announced its inaugural fund, Lifeforce Capital I, which closed at $50 million in 2021, demonstrating their commitment and capacity to support a focused portfolio of digital health innovators.

Beyond capital, Lifeforce Capital positions itself as a strategic partner, offering operational guidance, industry expertise, and access to a robust network of healthcare professionals and entrepreneurs. This hands-on approach is designed to help portfolio companies navigate the complex healthcare landscape, accelerate product development, achieve market validation, and scale their operations effectively, contributing to the broader evolution of healthcare.

Investor Profile

Lifeforce Capital has backed more than 51 startups, with 0 new investments in the last 12 months alone. The firm has led 6 rounds, about 12% of its total and boasts 7 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series A, Series B, Seed rounds (top funding stages).
  • Majority of deals are located in United States, United Kingdom.
  • Strong thematic focus on Health Care, Biotechnology, Medical.
  • Typical check size: $1M – $5M.

Stage Focus

  • Series A (41%)
  • Series B (20%)
  • Seed (18%)
  • Series C (10%)
  • Series Unknown (6%)
  • Post Ipo Equity (2%)
  • Private Equity (2%)
  • Series D (2%)

Country Focus

  • United States (94%)
  • United Kingdom (6%)

Industry Focus

  • Health Care
  • Biotechnology
  • Medical
  • Therapeutics
  • Pharmaceutical
  • Software
  • Health Diagnostics
  • Hospital
  • Machine Learning
  • Life Science
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Lifeforce Capital frequently co-invest with?

First Round Capital
North America, California, United States, San Francisco
Co-Investments: 5
Alexandria Venture Investments
North America, California, United States, Pasadena
Co-Investments: 5
Google Ventures
North America, California, United States, Mountain View
Co-Investments: 5
IV
North America, California, United States, San Francisco
Co-Investments: 6
Refactor
North America, California, United States, Burlingame
Co-Investments: 4
Casdin Capital
North America, New York, United States, New York
Co-Investments: 6
8VC
North America, California, United States, San Francisco
Co-Investments: 5
Section 32
North America, California, United States, San Diego
Co-Investments: 6
Threshold
North America, California, United States, Menlo Park
Co-Investments: 6
ARCH Venture Partners
North America, Illinois, United States, Chicago
Co-Investments: 5

Which angels does Lifeforce Capital often collaborate with?

CG
North America, Utah, United States, Salt Lake City
Shared Deals: 2
SI
North America, Colorado, United States, Denver
Shared Deals: 1
JW
North America, California, United States, Mountain View
Shared Deals: 1
BS
North America, California, United States, San Francisco
Shared Deals: 1
HT
North America, California, United States, San Francisco
Shared Deals: 2
MA
North America, California, United States, San Francisco
Shared Deals: 2
Matthew Winkler
North America, Texas, United States, Austin
Shared Deals: 1
AK
North America, Massachusetts, United States, Boston
Shared Deals: 1
David Hodgson
North America, New York, United States, New York
Shared Deals: 1
MC
North America, New York, United States, New York
Shared Deals: 2

What are some of recent deals done by Lifeforce Capital?

Vilya

Seattle, Washington, United States

Vilya is a biotechnology company developing a novel class of drugs that precisely target the biology of disease.

BiotechnologyHealth DiagnosticsLife ScienceMedical
Series AJun 4, 2024
Amount Raised: $21,000,000
Ochre Bio

Oxford, Oxfordshire, United Kingdom

Ochre Bio is a biotechnology company that develops and builds a deep phenotyping platform to rejuvenate transplant livers.

BiopharmaBiotechnologyHealth CareTherapeutics
Series AOct 10, 2022
Amount Raised: $30,000,000
Transition Bio

Cambridge, Massachusetts, United States

Transition Bio provides condensate technology for drug discovery and diagnostics.

BiotechnologyHealth CareHealth DiagnosticsMedical
Series AJun 2, 2022
Amount Raised: $50,000,000
MindRight Health

Newark, New Jersey, United States

MindRight Health offers culturally-responsive mental health coaching over a text message.

Health CareMental HealthPsychologySMS
SeedMay 24, 2022
Amount Raised: $1,780,000
Character Biosciences

Jersey City, New Jersey, United States

Biopharmaceutical research and development company

BiotechnologyClinical TrialsHealth CareHealth DiagnosticsPharmaceutical
Series AMay 17, 2022
Amount Raised: $18,000,000
Aspen Neuroscience

San Diego, California, United States

Aspen Neuroscience is a biotechnology company that specializes in personalized cell therapies.

BiotechnologyMedicalPharmaceuticalTherapeutics
Series BMay 9, 2022
Amount Raised: $147,500,000
Cylinder

Chicago, Illinois, United States

Cylinder is a digital health company that offers personalized care for people with digestive conditions.

Health CareTelehealthWellness
Series AMar 8, 2022
Amount Raised: $16,000,000
Synapticure

Chicago, Illinois, United States

We provide neurodegenerative disease patients with expert MDs and 24/7 wrap around care, no matter where you live in the US

Health CareMedicalNeuroscienceWellness
SeedFeb 2, 2022
Amount Raised: $6,000,000
64x Bio

San Francisco, California, United States

64x Bio builds a platform that increases the speed and scale of mammalian cell line discovery.

BiopharmaBiotechnologyGeneticsLife SciencePharmaceutical
Series AJan 19, 2022
Amount Raised: $55,000,000
PostEra

Boston, Massachusetts, United States

PostEra is building a modern 21st century biopharma. We're using our advances in machine learning to bring more cures to patients

Artificial Intelligence (AI)BiotechnologyMachine LearningPharmaceuticalTherapeutics
Series AJan 11, 2022
Amount Raised: $24,000,000