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Matrix Capital Management

North America, Massachusetts, United States, Waltham

Description

Matrix Capital Management is an employee-owned investment firm established in 1999 and headquartered in Waltham, Massachusetts. Primarily recognized as a hedge fund, the firm focuses on long-term investments across both public and private equity markets. Their investment philosophy is rooted in rigorous fundamental research, aiming to identify high-growth companies with significant long-term potential. This approach leads them to take concentrated positions in a select number of companies, a strategy that distinguishes them from many diversified investment funds.

While widely known for their substantial holdings in publicly traded companies, Matrix Capital Management also actively participates in private equity markets. Their private investment strategy typically involves late-stage, high-growth companies, often those poised for an initial public offering (IPO). They are not a traditional early-stage venture capital firm, but rather a growth equity investor that seeks to partner with companies before or during their transition to public markets. Notable examples of their pre-IPO investments include technology giants like Snowflake, Marvell Technology, Nvidia, and Palo Alto Networks, demonstrating their focus on disruptive and market-leading innovators.

Matrix Capital Management manages billions of dollars in assets, with public equity holdings alone exceeding $7 billion as of late 2023, reflecting their significant capital deployment capabilities. Their involvement in private rounds is often substantial, contributing to large funding rounds for mature private companies. However, due to the opportunistic and often confidential nature of hedge fund private investments, specific typical 'first cheque' sizes are not publicly disclosed or consistently defined in the same manner as traditional venture capital firms. Their investments are tailored to the specific opportunity and the capital needs of late-stage companies, rather than adhering to a fixed range for early-stage funding.

Investor Profile

Matrix Capital Management has backed more than 41 startups, with 1 new investments in the last 12 months alone. The firm has led 22 rounds, about 54% of its total and boasts 7 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series B, Series C, Series A rounds (top funding stages).
  • Majority of deals are located in United States, New Zealand.
  • Strong thematic focus on Biotechnology, Health Care, Life Science.

Stage Focus

  • Series B (27%)
  • Series C (24%)
  • Series A (22%)
  • Series D (7%)
  • Post Ipo Equity (7%)
  • Seed (5%)
  • Series Unknown (5%)
  • Series F (2%)

Country Focus

  • United States (93%)
  • New Zealand (7%)

Industry Focus

  • Biotechnology
  • Health Care
  • Life Science
  • Software
  • Pharmaceutical
  • Biopharma
  • Therapeutics
  • Artificial Intelligence (Ai)
  • Medical Device
  • Genetics
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Matrix Capital Management frequently co-invest with?

OrbiMed
North America, New York, United States, New York
Co-Investments: 5
M
North America, California, United States, San Francisco
Co-Investments: 8
Surveyor Capital
North America, Illinois, United States, Chicago
Co-Investments: 8
Pfizer Venture Investments
North America, New York, United States, New York
Co-Investments: 3
Samsara BioCapital
North America, California, United States, Palo Alto
Co-Investments: 5
SoftBank Vision Fund
Europe, England, United Kingdom, London
Co-Investments: 5
NTT Venture Capital
North America, California, United States, Menlo Park
Co-Investments: 5
Decheng Capital
North America, California, United States, Menlo Park
Co-Investments: 4
Takeda Ventures
North America, California, United States, San Diego
Co-Investments: 3
Mayo Clinic Ventures
North America, Minnesota, United States, Rochester
Co-Investments: 5

Which angels does Matrix Capital Management often collaborate with?

BC
North America, California, United States, San Francisco
Shared Deals: 1

What are some of recent deals done by Matrix Capital Management?

Anumana

Cambridge, Massachusetts, United States

Anumana develops AI-driven ECG algorithms for early cardiovascular diagnosis and care.

Artificial Intelligence (AI)Health CareHealth DiagnosticsMedical Device
Series CApr 24, 2025
Rivos

Santa Clara, California, United States

Rivos is a high-performance RISC-V system startup targeting integrated system solutions for enterprises.

HardwareIndustrial ManufacturingManufacturing
Series AApr 16, 2024
Amount Raised: $250,000,000
Alumis

San Francisco, California, United States

Alumis is a precision medicine company focused on the discovery, development and treatment of autoimmune disorders.

BiotechnologyHealth CareLife SciencePrecision Medicine
Series CMar 6, 2024
Amount Raised: $259,000,000
ReCode Therapeutics

Dallas, Texas, United States

ReCode Therapeutics is a genetic medicines company that specializes in mRNA and gene correction therapeutics.

BiopharmaBiotechnologyGeneticsPharmaceutical
Series BSep 19, 2023
Amount Raised: $50,000,000
AltPep

Seattle, Washington, United States

AltPep provides a novel approach for tackling amyloid diseases, with diagnostic, therapeutic and anti-biofilm applications.

Biotechnology
Series BJun 22, 2023
Amount Raised: $52,900,000
ElevateBio

Waltham, Massachusetts, United States

ElevateBio is a biotechnology company that specializes in cell and gene-based therapies.

Alternative MedicineBiotechnologyInformation Technology
Series DMay 24, 2023
Amount Raised: $401,000,000
ACELYRIN

Los Angeles, California, United States

ACELYRIN is a biopharma company that identifies, acquires, and accelerates the development and commercialization of life-changing therapies.

BiopharmaBiotechnologyHealth Care
Series CSep 13, 2022
Amount Raised: $300,000,000
Monod Bio

Seattle, Washington, United States

Monod Bio is a life sciences company developing biosensors for protein and other analyte detection.

BiotechnologyHealth CareLife ScienceMedical
SeedAug 15, 2022
Amount Raised: $25,000,000
ReCode Therapeutics

Dallas, Texas, United States

ReCode Therapeutics is a genetic medicines company that specializes in mRNA and gene correction therapeutics.

BiopharmaBiotechnologyGeneticsPharmaceutical
Series BJun 29, 2022
Amount Raised: $120,000,000
Talos

New York, New York, United States

Talos is an end-to-end crypto trading platform that provides digital asset trading technology for lenders, brokers, and investors.

CryptocurrencyFinancial ServicesFinTechTrading Platform
Series BMay 10, 2022
Amount Raised: $105,000,000