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Mayo Clinic

North America, Minnesota, United States, Rochester

Description

Mayo Clinic, a globally renowned nonprofit academic medical center based in Rochester, Minnesota, extends its mission of patient care, education, and research into the venture capital landscape through Mayo Clinic Ventures. This dedicated arm strategically invests in early-stage companies developing innovative technologies that align with Mayo Clinic's core objectives. Their investment focus spans critical areas such as digital health solutions, advanced medical devices, novel therapeutics, and precision diagnostics, aiming to accelerate the translation of promising research into clinical practice and commercial success.

Mayo Clinic Ventures acts as more than just a capital provider; it offers portfolio companies unparalleled access to Mayo Clinic's vast clinical expertise, research infrastructure, and patient populations. This unique value proposition includes opportunities for clinical validation, scientific collaboration, and strategic guidance from leading medical experts. The team actively seeks out companies that can significantly impact healthcare delivery, improve patient outcomes, and contribute to Mayo Clinic's long-term strategic goals, often co-investing with traditional venture capital firms and corporate partners.

The venture arm has built a substantial portfolio, reportedly comprising over 100 companies across various stages of development, demonstrating its sustained commitment to healthcare innovation. While investment sizes can vary based on the stage and strategic importance of the opportunity, Mayo Clinic Ventures typically provides initial checks ranging from $1 million to $5 million for early-stage companies. These investments are often part of larger syndicated rounds, reflecting their preference for collaborative funding models. Their strategic approach emphasizes long-term partnerships and the potential for significant clinical and commercial impact, rather than purely financial returns.

The strategic investments made by Mayo Clinic Ventures underscore the institution's forward-thinking approach to healthcare innovation. By leveraging its deep clinical and research capabilities, Mayo Clinic not only supports the growth of promising startups but also ensures that cutting-edge technologies are developed and integrated into patient care, ultimately benefiting a broader population and reinforcing its leadership in medical advancement.

Investor Profile

Mayo Clinic has backed more than 88 startups, with 5 new investments in the last 12 months alone. The firm has led 13 rounds, about 15% of its total and boasts 12 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series A, Series B, Seed rounds (top funding stages).
  • Majority of deals are located in United States, Israel, Canada.
  • Strong thematic focus on Health Care, Biotechnology, Medical.
  • Typical check size: $1M – $5M.

Stage Focus

  • Series A (27%)
  • Series B (24%)
  • Seed (18%)
  • Series Unknown (8%)
  • Series C (8%)
  • Series D (5%)
  • Corporate Round (3%)
  • Convertible Note (3%)
  • Pre Seed (1%)
  • Non Equity Assistance (1%)

Country Focus

  • United States (85%)
  • Israel (3%)
  • Canada (2%)
  • Sweden (1%)
  • India (1%)
  • Switzerland (1%)
  • South Korea (1%)
  • China (1%)
  • United Kingdom (1%)
  • The Netherlands (1%)

Industry Focus

  • Health Care
  • Biotechnology
  • Medical
  • Artificial Intelligence (Ai)
  • Software
  • Health Diagnostics
  • Medical Device
  • Therapeutics
  • Pharmaceutical
  • Machine Learning
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Mayo Clinic frequently co-invest with?

Sequoia Capital
North America, California, United States, Menlo Park
Co-Investments: 5
Canaan Partners
North America, California, United States, Menlo Park
Co-Investments: 5
Kleiner Perkins
North America, California, United States, Menlo Park
Co-Investments: 3
Alexandria Venture Investments
North America, California, United States, Pasadena
Co-Investments: 4
Kaiser Permanente Ventures
North America, California, United States, Oakland
Co-Investments: 5
Three Arch Partners
North America, California, United States, Portola Valley
Co-Investments: 5
Bay City Capital
North America, California, United States, San Francisco
Co-Investments: 5
MPM Capital
North America, Massachusetts, United States, Boston
Co-Investments: 5
Aberdare Ventures
North America, California, United States, San Francisco
Co-Investments: 5
Social Capital
North America, California, United States, Menlo Park
Co-Investments: 4

Which angels does Mayo Clinic often collaborate with?

AC
North America, California, United States, Los Altos
Shared Deals: 1
AS
North America, United States
Shared Deals: 1
HB
North America, New York, United States, New York
Shared Deals: 1
Marius Nacht
Asia, Tel Aviv, Israel, Tel Aviv-yafo
Shared Deals: 1
NB
North America, California, United States, San Francisco
Shared Deals: 1
MG
North America, California, United States, San Francisco
Shared Deals: 1
Matthew Winkler
North America, Texas, United States, Austin
Shared Deals: 1
Shared Deals: 1
NH
North America, California, United States, San Francisco
Shared Deals: 1
KD
North America, California, United States, Oakland
Shared Deals: 1

What are some of recent deals done by Mayo Clinic?

Delfina

San Francisco, California, United States

Delfina provides a personalized prenatal care system that uses the power of data to keep moms and babies safe during pregnancy.

Health CareMedicalPersonal HealthService IndustryWellness
Series AJan 28, 2025
Amount Raised: $17,000,000
Scaled Insights

Toronto, Ontario, Canada

SI invented "Behavioural AI" which it uses to help clinicians convince their patients towards healthier behaviours

Artificial Intelligence (AI)ComputerHealth CareMedicalSoftware
SeedDec 7, 2024
Jupiter BioVentures

Delaware City, Delaware, United States

Jupiter BioVentures is a creation engine company that focuses on de-risking early-stage projects.

BiotechnologyTherapeutics
Series UnknownNov 19, 2024
Amount Raised: $70,000,000
Aignostics

Berlin, Berlin, Germany

Aignostics is an AI-powered precision diagnostics focused on pathology to assist with drug development and clinical research.

Artificial Intelligence (AI)Health CareHealth DiagnosticsMachine LearningSoftware
Series BOct 29, 2024
Amount Raised: $34,000,000
Clarapath

New York, New York, United States

Clarapath is a medical robotics company that develops the SectionStar, a platform to mimic the human histotechnician.

BiotechnologyHealth CareMedical
Series BJul 24, 2024
Amount Raised: $36,000,000
Endogenex

Plymouth, Minnesota, United States

Endogenex develops an endoscopic procedure to help patients with type 2 diabetes regain control of their blood glucose levels.

Health CareMedical DeviceTherapeutics
Series CJun 25, 2024
Amount Raised: $88,000,000
PinkDx

Indianapolis, Indiana, United States

PinkDx is a biotechnology company.

BiopharmaBiotechnology
Series AApr 25, 2024
Amount Raised: $40,000,000
Collaborative Robotics

Santa Clara, California, United States

Collaborative Robotics is building robots that help in indoor and outdoor tasks alongside humans.

Information TechnologyMachinery ManufacturingRobotics
Series BApr 10, 2024
Amount Raised: $100,000,000
UpDoc

Palo Alto, California, United States

UpDoc is a technology-enabled services company that offers the first-ever proprietary conversational AI platform for autonomous.

Artificial Intelligence (AI)Hospital
SeedJan 5, 2024
vMocion

Los Angeles, California, United States

Putting the Motion in Virtual Reality™

SoftwareVirtual Reality
SeedJan 3, 2024
Amount Raised: $3,000,000