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MPM Capital

North America, Massachusetts, United States, Boston

Description

MPM Capital is a prominent healthcare investment firm based in Boston, United States, with a dedicated focus on biotechnology, particularly in developing therapeutic technologies for oncology and other areas of high unmet medical need. Established with a long history in the life sciences sector, the firm has successfully raised over $3 billion in capital across various funds, demonstrating significant financial capacity and commitment to the biotech ecosystem. Their investment philosophy centers on identifying and building innovative companies that aim to develop cures for major diseases, positioning them as a key player in advancing medical breakthroughs.

The firm employs a flexible investment strategy, deploying capital across all stages of company development, from initial company creation and early-stage ventures to late-stage private and even public companies. MPM Capital is known for taking an active role in its portfolio companies, often leading or co-leading financing rounds. This hands-on approach underscores their commitment to fostering the growth and success of the companies they back, leveraging their deep industry expertise and extensive network to guide therapeutic development. Their portfolio spans more than 130 companies, reflecting a broad and impactful reach within the biotechnology landscape.

MPM Capital continues to be an active investor, as evidenced by the closing of its BioVentures 2021 fund at $850 million, providing substantial capital for new investments. This significant fund size allows MPM to make substantial commitments to its portfolio companies, often participating in large financing rounds. While specific check sizes can vary widely depending on the stage and needs of the company, their role as lead or co-lead investors in multi-million dollar rounds suggests a capacity for significant capital deployment. Based on their fund sizes and typical deal structures in the biotech sector, MPM Capital's initial investments generally range from approximately $10 million for early-stage or company creation efforts, extending up to $75 million for leading later-stage or more mature opportunities.

This strategic approach, combined with substantial financial resources and a specialized focus, solidifies MPM Capital's position as a leading venture capital firm in the biotechnology space. Their commitment to addressing critical medical needs through strategic investments makes them a vital partner for innovative therapeutic companies globally.

Investor Profile

MPM Capital has backed more than 291 startups, with 1 new investments in the last 12 months alone. The firm has led 89 rounds, about 31% of its total and boasts 99 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series B, Series A, Series C rounds (top funding stages).
  • Majority of deals are located in United States, Canada, United Kingdom.
  • Strong thematic focus on Biotechnology, Health Care, Pharmaceutical.
  • Typical check size: $10M – $75M.

Stage Focus

  • Series B (26%)
  • Series A (25%)
  • Series C (19%)
  • Series Unknown (10%)
  • Series D (8%)
  • Series E (3%)
  • Seed (3%)
  • Post Ipo Equity (2%)
  • Private Equity (2%)

Country Focus

  • United States (92%)
  • Canada (2%)
  • United Kingdom (1%)
  • Italy (1%)
  • Germany (1%)
  • Taiwan (1%)

Industry Focus

  • Biotechnology
  • Health Care
  • Pharmaceutical
  • Therapeutics
  • Medical
  • Biopharma
  • Medical Device
  • Health Diagnostics
  • Life Science
  • Manufacturing
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does MPM Capital frequently co-invest with?

OrbiMed
North America, New York, United States, New York
Co-Investments: 28
Abingworth
Europe, England, United Kingdom, London
Co-Investments: 19
InterWest Partners
North America, California, United States, Menlo Park
Co-Investments: 16
New Enterprise Associates
North America, California, United States, Menlo Park
Co-Investments: 24
HealthCare Ventures
North America, Massachusetts, United States, Cambridge
Co-Investments: 15
Versant Ventures
North America, California, United States, Menlo Park
Co-Investments: 21
Frazier Healthcare Partners
North America, Washington, United States, Seattle
Co-Investments: 17
Bessemer Venture Partners
North America, California, United States, San Francisco
Co-Investments: 13
Advanced Technology Ventures
North America, California, United States, Menlo Park
Co-Investments: 17
ARCH Venture Partners
North America, Illinois, United States, Chicago
Co-Investments: 23

Which angels does MPM Capital often collaborate with?

GH
North America, Missouri, United States, Ozark
Shared Deals: 1
GF
North America, California, United States
Shared Deals: 2
GR
North America, Wisconsin, United States, Milwaukee
Shared Deals: 1
Shared Deals: 1
JM
North America, United States
Shared Deals: 1
SB
North America, California, United States, Los Altos
Shared Deals: 1
AW
North America, California, United States, San Francisco
Shared Deals: 1
SB
Europe, England, United Kingdom, London
Shared Deals: 1
YM
North America, California, United States, Los Altos Hills
Shared Deals: 1
FB
North America, New York, United States, New York
Shared Deals: 1

What are some of recent deals done by MPM Capital?

Umoja Biopharma

Seattle, Washington, United States

Umoja Biopharma is a biopharmaceutical company developing next-generation immunotherapies intended to combat cancer.

BiopharmaBiotechnologyDeveloper Platform
Series CJan 14, 2025
Amount Raised: $100,000,000
āshibio

Brisbane, California, United States

āshibio is a privately held biotechnology business exploring innovative therapies to treat bone and connective tissue ailments.

BiotechnologyMedical DeviceTherapeutics
Series AJun 20, 2024
Amount Raised: $40,000,000
Reunion Neuroscience

Toronto, Ontario, Canada

Reunion Neuroscience is a clinical-stage pharmaceutical company developing therapeutic solutions for underserved mental health conditions.

BiotechnologyMental HealthPharmaceutical
Series AMay 2, 2024
Amount Raised: $103,000,000
Frontier Medicines

San Francisco, California, United States

Frontier Medicines is a biopharmaceutical company that develops a chemoproteomics platform to accelerate the development of medicines.

BiopharmaBiotechnologyLife SciencePharmaceuticalPrecision Medicine
Series CFeb 22, 2024
Amount Raised: $80,000,000
Firefly Bio

San Francisco, California, United States

Firefly Bio specializes in Degrader Antibody Conjugates (DACs) which combine the unique strengths of ADCs with selective protein degraders.

BiotechnologyMedical
Series AFeb 15, 2024
Amount Raised: $94,000,000
NextPoint Therapeutics

Cambridge, Massachusetts, United States

NextPoint Therapeutics is a clinical-stage biotechnology company that develops therapeutics to treat cancer patients.

BiotechnologyHealth CareLife ScienceTherapeutics
Series BFeb 14, 2024
Amount Raised: $42,500,000
AstronauTx

Reading, Reading, United Kingdom

AstronauTx is a UCL spin-off, will develop medicines designed to reset the behaviour of astrocytes.

BiotechnologyPharmaceutical
Series AOct 8, 2023
Amount Raised: $58,653,248
Deka Biosciences

Germantown, Maryland, United States

Early stage biotechnology company

BiotechnologyHealth Care
Series BSep 28, 2023
Amount Raised: $20,000,000
ReCode Therapeutics

Dallas, Texas, United States

ReCode Therapeutics is a genetic medicines company that specializes in mRNA and gene correction therapeutics.

BiopharmaBiotechnologyGeneticsPharmaceutical
Series BSep 19, 2023
Amount Raised: $50,000,000
Arialys Therapeutics

La Jolla, California, United States

Arialys Therapeutics is a pre-clinical stage company that develops auto-antibody focusing on neuroscience.

Health CareMedicalTherapeutics
SeedSep 12, 2023
Amount Raised: $58,000,000