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Northpond Ventures

North America, Maryland, United States, Bethesda

Description

Northpond Ventures is a prominent science-driven venture capital firm based in Bethesda, Maryland, with a strong focus on transformative technologies within the life sciences and deep technology sectors. Founded with the mission to build, advise, and invest in companies developing breakthrough innovations, Northpond distinguishes itself by its commitment to scientific rigor and long-term value creation. The firm's investment thesis centers on areas poised for significant disruption, leveraging scientific advancements to address critical challenges and create new markets.

The firm's investment strategy is bifurcated into two core pillars: Life Sciences and Deep Tech. Within Life Sciences, Northpond actively seeks opportunities across genomics, proteomics, diagnostics, therapeutics, tools & services, and digital health, supporting companies that are pioneering new approaches to human health and biological understanding. On the Deep Tech side, their interests span advanced materials, artificial intelligence, robotics, quantum technologies, photonics, and advanced manufacturing. This dual focus allows Northpond to capitalize on the convergence of scientific discovery and technological innovation, backing companies from early-stage development through growth-stage expansion.

Northpond Ventures has demonstrated significant fundraising success, reflecting its strong market position and investor confidence. The firm notably closed its fourth flagship fund, Northpond Ventures IV, at $500 million in 2023, following its equally successful Northpond Ventures III, which also raised $500 million in 2021. These substantial fund sizes enable Northpond to deploy significant capital into its portfolio companies. While specific initial check sizes can vary based on stage and opportunity, Northpond typically writes first checks ranging from approximately $5 million for promising early-stage ventures to $30 million for leading or co-leading Series A, B, and select growth rounds, often reserving substantial capital for follow-on investments.

Beyond capital, Northpond Ventures takes an active, hands-on approach, providing strategic guidance, operational support, and access to a vast network of scientific and industry experts. Their team comprises seasoned investors, scientists, and entrepreneurs, fostering a collaborative environment aimed at accelerating the development and commercialization of complex technologies. This comprehensive support system is designed to help portfolio companies navigate the intricate pathways from scientific discovery to market leadership, underscoring Northpond's commitment to fostering enduring value and impactful innovation in the science and technology landscape.

Investor Profile

Northpond Ventures has backed more than 123 startups, with 7 new investments in the last 12 months alone. The firm has led 74 rounds, about 60% of its total and boasts 14 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series A, Series B, Series C rounds (top funding stages).
  • Majority of deals are located in United States, United Kingdom, Australia.
  • Strong thematic focus on Biotechnology, Health Care, Medical.
  • Led 3 rounds in the past year.
  • Typical check size: $5M – $30M.

Stage Focus

  • Series A (38%)
  • Series B (24%)
  • Series C (17%)
  • Series D (6%)
  • Series Unknown (6%)
  • Seed (4%)
  • Series E (2%)
  • Post Ipo Equity (1%)
  • Series H (1%)
  • Series G (1%)

Country Focus

  • United States (89%)
  • United Kingdom (3%)
  • Australia (3%)
  • Switzerland (2%)
  • Canada (2%)

Industry Focus

  • Biotechnology
  • Health Care
  • Medical
  • Health Diagnostics
  • Life Science
  • Therapeutics
  • Software
  • Pharmaceutical
  • Information Technology
  • Bioinformatics
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Northpond Ventures frequently co-invest with?

OrbiMed
North America, New York, United States, New York
Co-Investments: 6
Alexandria Venture Investments
North America, California, United States, Pasadena
Co-Investments: 7
Novalis LifeSciences
North America, Virginia, United States, Hampton
Co-Investments: 5
RA Capital Management
North America, Massachusetts, United States, Boston
Co-Investments: 7
Tao Capital Partners
North America, California, United States, San Francisco
Co-Investments: 8
CH
North America, New York, United States, New York
Co-Investments: 6
Sands Capital Ventures
North America, Virginia, United States, Arlington
Co-Investments: 15
Alumni Ventures
North America, New Hampshire, United States, Manchester
Co-Investments: 5
Section 32
North America, California, United States, San Diego
Co-Investments: 8
ARCH Venture Partners
North America, Illinois, United States, Chicago
Co-Investments: 11

Which angels does Northpond Ventures often collaborate with?

CG
North America, Utah, United States, Salt Lake City
Shared Deals: 1
David R. Walt
North America, Massachusetts, United States, Boston
Shared Deals: 2
Balaji Srinivasan
Asia, Central Region, Singapore, Singapore
Shared Deals: 1
MC
North America, North Dakota, United States, Fargo
Shared Deals: 2
MZ
North America, United States
Shared Deals: 1
MA
North America, California, United States, San Francisco
Shared Deals: 1
Andrew Keys
North America, Puerto Rico
Shared Deals: 2
CL
North America, California, United States, San Francisco
Shared Deals: 1
JB
North America, North Dakota, United States, Fargo
Shared Deals: 1
PS
North America, United States
Shared Deals: 1

What are some of recent deals done by Northpond Ventures?

Outcomes4Me

Boston, Massachusetts, United States

Outcomes4Me develops direct-to-patient AI-driven platform designed to assist cancer patients in managing their care.

Artificial Intelligence (AI)Health CareMedicalOncologyPersonal HealthSoftware
Series UnknownMay 29, 2025
Amount Raised: $21,000,000
QbDVision

Austin, Texas, United States

QbDVision is a biopharma company that offers a platform designed specifically for biotech products, teams, and processes.

BiotechnologyHealth CareInformation TechnologyManufacturing
Series AMay 1, 2025
Amount Raised: $13,000,000
Garuda Therapeutics

Cambridge, Massachusetts, United States

Garuda Therapeutics develops off-the-shelf hematopoietic stem cell therapies to treat severe and life-threatening diseases.

BiotechnologyHealth CareLife ScienceTherapeutics
Series AMar 4, 2025
Amount Raised: $50,000,000
EnPlusOne Biosciences

Watertown, Massachusetts, United States

EnPlusOne Biosciences provides innovative solutions for emerging RNA therapeutics.

BiotechnologyLife ScienceTherapeutics
Series UnknownFeb 19, 2025
Amount Raised: $10,000,000
Vizgen

Cambridge, Massachusetts, United States

Vizgen is a biotech company that develops solutions for next-generation spatially resolved, single-cell transcriptomics.

BiotechnologyHealth CareLife ScienceMedical
Series DOct 9, 2024
VieCure

Denver, Colorado, United States

VieCure built an engine to turn data into knowledge and take the world’s best thinking to clinicians and patients in real time.

AnalyticsHealth CareHospital
Series UnknownSep 30, 2024
Amount Raised: $45,000,000
Inflammatix

Burlingame, California, United States

Inflammatix develops rapid immune system diagnostics to improve patient care and public health.

BioinformaticsBiotechnologyHealth CareHealth Diagnostics
Series ESep 12, 2024
Amount Raised: $57,000,000
SeLux Diagnostics

Charlestown, Massachusetts, United States

SeLux Diagnostics is a developer of a next-generation phenotyping platform that provides personalized antimicrobial therapies to patients.

BiotechnologyHealth CareHealth DiagnosticsTherapeutics
Series DApr 1, 2024
Amount Raised: $48,000,000
Elephas

Madison, Wisconsin, United States

Elephas harnesses latest advances in cancer biology, multimodal microscopy, and artificial intelligence to empower clinical decision-making.

Artificial Intelligence (AI)BiotechnologyHealth CareHealth DiagnosticsMedical
Series CJan 24, 2024
Amount Raised: $55,000,000
Totus Medicines

Cambridge, Massachusetts, United States

Totus Medicines employs uses AI/ML and innovative DNA-encoded covalent library tech to discover small molecule medicines.

BiopharmaBiotechnologyMedical
Series BDec 15, 2023
Amount Raised: $66,000,000