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Small Business Innovation Research

North America, Alabama, United States, America

Description

The Small Business Innovation Research (SBIR) program is a highly significant, non-dilutive funding mechanism established by the U.S. federal government, designed to stimulate technological innovation among small businesses. It serves multiple objectives, including meeting federal research and development needs, fostering participation by small businesses in federally-funded R&D, and encouraging the commercialization of innovative technologies. Unlike traditional venture capital firms, SBIR provides grants or contracts rather than equity investments, making it an attractive option for early-stage companies seeking to de-risk their technology without relinquishing ownership.

The program operates through a competitive, three-phase structure. Phase I awards focus on establishing the scientific, technical, and commercial merit and feasibility of a proposed R&D effort, typically lasting 6-12 months. Successful Phase I projects can then apply for Phase II funding, which supports the principal R&D effort and aims to bring the technology closer to commercialization, usually over a 2-year period. Phase III involves the commercialization of the technology developed under Phases I and II, utilizing non-SBIR funds. Various federal agencies, including the Department of Defense, National Institutes of Health, and National Science Foundation, participate in the SBIR program, each with specific R&D needs and funding priorities.

Funding amounts vary considerably across the participating agencies and phases. For instance, federal agencies with an extramural R&D budget exceeding $100 million are mandated to set aside 3.2% of that budget for SBIR awards in fiscal year 2024. While Phase I awards generally range from $150,000 to $250,000, some agencies or specific solicitations may offer higher amounts, occasionally up to $1 million or more for specific topics or "Direct to Phase II" awards. Phase II awards are substantially larger, often ranging from $750,000 to $1.5 million, with some agencies providing awards exceeding $3 million, depending on the scope and agency. In fiscal year 2022 alone, the combined SBIR and STTR (Small Business Technology Transfer) programs awarded over $4 billion to small businesses across the nation, underscoring their critical role in the innovation ecosystem.

This program is a cornerstone for many deep tech and life science startups, providing crucial early-stage capital that often bridges the gap between academic research and private investment. Its non-dilutive nature allows founders to retain full equity while developing their technology, making it a powerful tool for small businesses to pursue high-risk, high-reward R&D that might otherwise struggle to attract conventional venture capital due to its early stage or specialized nature.

Investor Profile

Small Business Innovation Research has backed more than 133 startups, with 5 new investments in the last 12 months alone. The firm has led 99 rounds, about 74% of its total and boasts 9 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Grant, Seed, Series Unknown rounds (top funding stages).
  • Majority of deals are located in United States, India, Japan.
  • Strong thematic focus on Health Care, Biotechnology, Medical.
  • Led 4 rounds in the past year.
  • Typical check size: $150K – $250K.

Stage Focus

  • Grant (90%)
  • Seed (4%)
  • Series Unknown (2%)
  • Pre Seed (2%)
  • Angel (1%)
  • Non Equity Assistance (1%)

Country Focus

  • United States (96%)
  • India (2%)
  • Japan (1%)
  • Puerto Rico (1%)
  • Germany (1%)

Industry Focus

  • Health Care
  • Biotechnology
  • Medical
  • Software
  • Therapeutics
  • Manufacturing
  • Pharmaceutical
  • Medical Device
  • Artificial Intelligence (Ai)
  • Health Diagnostics
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Small Business Innovation Research frequently co-invest with?

Bill & Melinda Gates Foundation
North America, New York, United States, New York
Co-Investments: 1
National Institutes of Health
North America, Maryland, United States, Bethesda
Co-Investments: 9
National Institute of Allergy and Infectious Diseases
North America, Maryland, United States, Bethesda
Co-Investments: 2
U.S. Department of Defense
North America, District of Columbia, United States, Washington
Co-Investments: 2
Plug and Play
North America, California, United States, Sunnyvale
Co-Investments: 1
NASA
North America, District of Columbia, United States, Washington
Co-Investments: 1
Elevate Ventures
North America, Indiana, United States, Indianapolis
Co-Investments: 1
National Institute of Mental Health
North America, Maryland, United States, Bethesda
Co-Investments: 1
National Science Foundation
North America, Virginia, United States, Alexandria
Co-Investments: 6
US Department of Energy
North America, District of Columbia, United States, Washington
Co-Investments: 2

What are some of recent deals done by Small Business Innovation Research?

Ayuda Medical

Seattle, Washington, United States

Ayuda Medical is a medical device company that develops wearable devices and sensors to detect an overdose and call for help.

Health CareMedicalMedical Device
GrantDec 16, 2024
Amount Raised: $2,800,000
REI Systems

Sterling, Virginia, United States

REI Systems is a leading provider of web-based solutions to meet the complex business challenges of the public and private sector.

Cloud ComputingDevOpsEnterprise SoftwareOpen SourceSoftware
GrantDec 2, 2024
Amount Raised: $35,700,000
Teal Health

San Francisco, California, United States

Teal Health is a health tech company that develops cervical cancer screening and communication platforms.

Health CareHealth DiagnosticsMedical
GrantOct 17, 2024
Amount Raised: $1,680,000
skillsgapp

Greenville, South Carolina, United States

Skillsgapp connects youth to life-changing careers through geolocation mobile game play.

Career PlanningEducationGamingSoftware
GrantSep 20, 2024
Amount Raised: $275,000
IAMBIC

New York, New York, United States

AI-driven, precision-fit footwear. A TIME Best Invention of 2023.

Artificial Intelligence (AI)FashionMachine LearningRetail TechnologyShoes
GrantAug 2, 2024
Amount Raised: $1,000,000
bluShift Aerospace

Brunswick, Maine, United States

bluShift is a small space launch service that powers it rockets using a CO2-neutral biofuel

AerospaceCleanTechSpace Travel
GrantJun 4, 2024
Amount Raised: $1,000,000
Kinemo

Atlanta, Georgia, United States

Wearable body motion tracking

Assistive TechnologyHuman Computer InteractionMachine LearningMedical DeviceMotion CaptureSensorWearables
GrantMay 21, 2024
Amount Raised: $100,000
GSI Technology

Sunnyvale, California, United States

GSI Technology offers both Static Random Access Memory products (SRAMs) and Low Latency DRAM products (LLDRAM).

Information TechnologyManufacturingSemiconductor
GrantJan 3, 2024
Amount Raised: $1,100,000
Helical Fusion

Tokyo, Tokyo, Japan

Helical Fusion is a startup company that aims to commercialize fusion energy using magnetic confinement of high-temperature plasmas.

Clean EnergyEnergyEnergy EfficiencyRenewable Energy
GrantOct 17, 2023
Amount Raised: $13,354,366
A & P Technology

Cincinnati, Ohio, United States

A&P Technology is a manufacturer of braided fabrics.

Consumer GoodsManufacturingTextiles
GrantOct 12, 2023
Amount Raised: $1,245,479