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Woodline Partners

North America, California, United States, San Francisco

Description

Woodline Partners is a San Francisco-based investment firm with a primary focus on the healthcare and technology sectors, particularly known for its significant activity in biotechnology. Unlike traditional private equity firms that primarily engage in buyouts, Woodline operates as a "crossover" fund, actively investing in both public and private companies. This hybrid approach allows them to support promising businesses across various stages of their growth, from late-stage private rounds through their public market journey. The firm emphasizes a strategy rooted in deep fundamental research and a long-term investment horizon, aiming to partner with exceptional management teams to build market-leading businesses.

The firm's investment philosophy is geared towards identifying companies with strong potential for sustained growth and market leadership. Their portfolio showcases a clear preference for capital-intensive sectors like biotech, where they have participated in substantial funding rounds. For instance, Woodline was a key investor in Sana Biotechnology, participating in a massive $700 million Series A round in 2020, followed by a $350 million Series B later that year. This indicates their capacity and willingness to deploy significant capital into high-growth, innovative companies that require substantial funding to scale their operations and research.

Given their status as a multi-billion dollar investment firm, Woodline Partners typically deploys substantial capital in their private investments. While they are not known for leading early-stage seed or Series A rounds, they are significant participants in later-stage growth equity rounds for companies nearing or preparing for public market entry. Their typical first check size for private companies generally ranges from approximately $25 million to $150 million, reflecting their role as a major institutional investor in large, syndicated rounds. For example, they also participated in Recursion Pharmaceuticals' $436 million Series F round in 2021, further illustrating their commitment to substantial, later-stage investments in the life sciences.

Investor Profile

Woodline Partners has backed more than 65 startups, with 15 new investments in the last 12 months alone. The firm has led 4 rounds, about 6% of its total and boasts 30 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Post Ipo Equity, Series B, Series C rounds (top funding stages).
  • Majority of deals are located in United States, United Kingdom, Germany.
  • Strong thematic focus on Biotechnology, Health Care, Therapeutics.
  • Led 1 rounds in the past year.
  • Typical check size: $25M – $150M.

Stage Focus

  • Post Ipo Equity (48%)
  • Series B (22%)
  • Series C (11%)
  • Series A (6%)
  • Series D (5%)
  • Private Equity (3%)
  • Series F (3%)
  • Series Unknown (2%)
  • Post Ipo Debt (2%)

Country Focus

  • United States (88%)
  • United Kingdom (5%)
  • Germany (3%)
  • Canada (2%)
  • Japan (2%)
  • Sweden (2%)

Industry Focus

  • Biotechnology
  • Health Care
  • Therapeutics
  • Pharmaceutical
  • Medical
  • Life Science
  • Biopharma
  • Oncology
  • Information Technology
  • Precision Medicine
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Woodline Partners frequently co-invest with?

EcoR1 Capital
North America, California, United States, San Francisco
Co-Investments: 12
Surveyor Capital
North America, Illinois, United States, Chicago
Co-Investments: 13
Casdin Capital
North America, New York, United States, New York
Co-Investments: 10
RA Capital Management
North America, Massachusetts, United States, Boston
Co-Investments: 14
Deep Track Capital
North America, Connecticut, United States, Greenwich
Co-Investments: 11
Perceptive Advisors
North America, New York, United States, New York
Co-Investments: 11
Logos Capital
North America, California, United States, San Francisco
Co-Investments: 17
Janus Henderson Investors
Europe, England, United Kingdom, London
Co-Investments: 16
Fidelity
North America, Massachusetts, United States, Boston
Co-Investments: 10
Boxer Capital
North America, Florida, United States, Windermere
Co-Investments: 9

Which angels does Woodline Partners often collaborate with?

TG
Asia, Dubai, United Arab Emirates
Shared Deals: 2
DL
Europe, East Sussex, United Kingdom, Eastbourne
Shared Deals: 1
BT
North America, Massachusetts, United States, Marblehead
Shared Deals: 1
MY
North America, North Carolina, United States, Chapel Hill
Shared Deals: 2
ES
North America, New York, United States, New York
Shared Deals: 2
MF
North America, New York, United States, New York
Shared Deals: 2
Trevor Koverko
North America, Ontario, Canada, Toronto
Shared Deals: 1
AK
North America, California, United States, San Francisco
Shared Deals: 1

What are some of recent deals done by Woodline Partners?

SAB Biotherapeutics

Sioux Falls, South Dakota, United States

SAB Biotherapeutics is a clinical-stage biopharmaceutical development company.

BiotechnologyClinical TrialsTherapeutics
Post Ipo EquityJul 21, 2025
Amount Raised: $175,000,000
ProCap Financial

New York, New York, United States

ProCap Financial is a bitcoin-native financial services firm focused on building and funding companies that solve important problems.

BitcoinCryptocurrencyFinance
Post Ipo DebtJun 23, 2025
Amount Raised: $235,000,000
ProCap Financial

New York, New York, United States

ProCap Financial is a bitcoin-native financial services firm focused on building and funding companies that solve important problems.

BitcoinCryptocurrencyFinance
Post Ipo EquityJun 23, 2025
Amount Raised: $516,500,000
LEXEO Therapeutics

New York, New York, United States

LEXEO Therapeutics utilizes gene therapy to treat genetically defined cardiovascular and central nervous system diseases.

BiotechnologyLife ScienceTherapeutics
Post Ipo EquityMay 27, 2025
Amount Raised: $80,000,000
Rezolute

Louisville, Colorado, United States

Rezolute is a clinical-stage biopharma specializing in the development of drug therapies for patients with metabolic and orphan diseases.

BiotechnologyDiabetesHealth CareTherapeutics
Post Ipo EquityApr 23, 2025
Amount Raised: $96,900,000
Caris Life Sciences

Irving, Texas, United States

Caris Life Sciences develops molecular profiling and AI-driven technologies to support precision medicine in oncology.

Artificial Intelligence (AI)BiopharmaBiotechnologyHealth CareLife Science
Private EquityApr 7, 2025
Amount Raised: $168,000,000
Archive

Los Altos, California, United States

Archive is a technology company that builds innovative, scalable, and profitable resale businesses for global brands.

FashionMarketplaceRetail
Series BFeb 4, 2025
Amount Raised: $30,000,000
Tectonic Therapeutic

Allston, Massachusetts, United States

Tectonic Therapeutic is a biotechnology company which focuses on scientific research in biochemistry and molecular pharmacology.

Biotechnology
Post Ipo EquityFeb 3, 2025
Amount Raised: $185,000,000
Kala Pharmaceuticals

Waltham, Massachusetts, United States

Kala Pharmaceuticals develops novel treatments for diseases that affect mucosal tissues.

BiotechnologyHealth CareMedicalPharmaceutical
Post Ipo EquityDec 30, 2024
Amount Raised: $10,750,000
Olema Oncology

San Francisco, California, United States

Olema Oncology is a preclinical biotechnology company that develops new drugs for the treatment and prevention of breast cancer.

BiopharmaBiotechnologyHealth CareMedicalOncologyPharmaceutical
Post Ipo EquityDec 2, 2024
Amount Raised: $250,000,000