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Borealis Ventures

North America, New Hampshire, United States, Hanover

Description

Borealis Ventures is an early-stage venture capital firm strategically located in Hanover, New Hampshire, with a strong historical and ongoing affiliation with Dartmouth College and the broader Upper Valley innovation ecosystem. Established to foster groundbreaking companies, the firm primarily focuses its investments on the dynamic sectors of Information Technology and Life Sciences. Borealis Ventures is known for partnering closely with visionary entrepreneurs who are building market-defining companies from the ground up, often leveraging deep technological or scientific advancements.

The firm's investment strategy centers on providing crucial early-stage capital, typically leading or co-leading Seed and Series A financing rounds. Their approach extends beyond mere capital injection, emphasizing active collaboration and support to help portfolio companies navigate the challenges of early growth, product development, and market penetration. Borealis Ventures seeks out opportunities where their expertise and network can significantly accelerate a company's trajectory, particularly those with a clear path to disrupting established industries or creating entirely new markets.

Borealis Ventures has demonstrated a consistent ability to raise substantial capital, reflecting investor confidence in their strategy and team. For instance, their most recent fund, Borealis Ventures V, L.P., successfully closed at $100 million in 2021, contributing to their total capital under management exceeding $250 million across all funds. The firm has built a diverse portfolio, having made over 70 investments in promising startups across its target sectors. Their typical initial investment, or first cheque, ranges from $500,000 to $5,000,000, tailored to the specific needs and stage of the early-stage company. This flexible check size allows them to support a wide spectrum of ventures, from nascent seed-stage ideas to more developed Series A companies ready for significant scaling.

Investor Profile

Borealis Ventures has backed more than 51 startups, with 0 new investments in the last 12 months alone. The firm has led 9 rounds, about 18% of its total and boasts 14 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series A, Series B, Series C rounds (top funding stages).
  • Majority of deals are located in United States, United Kingdom.
  • Strong thematic focus on Software, Biotechnology, Health Care.
  • Typical check size: $500K – $5M.

Stage Focus

  • Series A (33%)
  • Series B (20%)
  • Series C (14%)
  • Series Unknown (12%)
  • Seed (10%)
  • Series D (8%)
  • Debt Financing (2%)
  • Series E (2%)

Country Focus

  • United States (94%)
  • United Kingdom (6%)

Industry Focus

  • Software
  • Biotechnology
  • Health Care
  • Enterprise Software
  • Construction
  • Therapeutics
  • Life Science
  • Manufacturing
  • E-commerce Platforms
  • Logistics
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Borealis Ventures frequently co-invest with?

OrbiMed
North America, New York, United States, New York
Co-Investments: 8
Needham Capital Partners
North America, New York, United States, New York
Co-Investments: 4
Egan-Managed Capital
North America, Massachusetts, United States, Boston
Co-Investments: 5
Village Ventures
North America, Massachusetts, United States, Williamstown
Co-Investments: 6
SV Health Investors
North America, Massachusetts, United States, Boston
Co-Investments: 5
PJC
North America, Massachusetts, United States, Boston
Co-Investments: 5
Google Ventures
North America, California, United States, Mountain View
Co-Investments: 5
North Bridge Venture Partners & Growth Equity
North America, Massachusetts, United States, Wellesley
Co-Investments: 8
Polaris Partners
North America, Massachusetts, United States, Boston
Co-Investments: 9
Kodiak Venture Partners
North America, Massachusetts, United States, Wellesley
Co-Investments: 8

Which angels does Borealis Ventures often collaborate with?

ZW
North America, New York, United States, New York
Shared Deals: 1
WC
North America, New York, United States, Manhattan
Shared Deals: 1
NT
North America, New York, United States, New York
Shared Deals: 1
Shared Deals: 1
David Shaw
North America, Maine, United States, Portland
Shared Deals: 1
George Godula
Asia, Shanghai, China, Shanghai
Shared Deals: 1
Daniel Yates
North America, District of Columbia, United States, Washington
Shared Deals: 1
MK
North America, California, United States, Stanford
Shared Deals: 1
AS
North America, New York, United States, New York
Shared Deals: 1
DS
North America, Maine, United States, Portland
Shared Deals: 1

What are some of recent deals done by Borealis Ventures?

ASTRA Therapeutics

Villigen, Aargau, Switzerland

ASTRA Therapeutics is a medication development business that uses cutting-edge science and technology.

Health CareTherapeutics
SeedJul 24, 2025
Amount Raised: $9,465,263
Ankyra

Boston, Massachusetts, United States

Ankyra is a biotech company developing anchored immunotherapy for cancer treatments.

BiotechnologyOncology
Series BNov 12, 2021
Amount Raised: $45,000,000
Orbit Discovery

Oxford, Oxfordshire, United Kingdom

Orbit Discovery is a peptide display company identifying potential peptide drugs for a range of chronic diseases.

BiotechnologyHealth CareManufacturing
SeedJul 20, 2021
Amount Raised: $7,607,445
Ovation

Cambridge, Massachusetts, United States

Ovation is a scientific data company providing a cloud-based LIMS for molecular diagnostic laboratories.

Cloud ComputingCloud Data ServicesCloud InfrastructureCloud ManagementEnterprise SoftwareLife ScienceManagement Information SystemsMedical
Series BDec 16, 2020
Amount Raised: $21,500,000
FidoCure

Palo Alto, California, United States

One Health Company specializes in genetic sequencing and diagnostic testing for animals.

Health CareMedicalVeterinary
Series AOct 29, 2020
Amount Raised: $10,000,000
Compass Therapeutics, Inc.

Boston, Massachusetts, United States

Compass Therapeutics is a biopharmaceutical company that focuses on drugging the immune system to treat human diseases.

BiopharmaBiotechnologyTherapeutics
Series UnknownJul 1, 2020
Amount Raised: $60,482,210
Ovation

Cambridge, Massachusetts, United States

Ovation is a scientific data company providing a cloud-based LIMS for molecular diagnostic laboratories.

Cloud ComputingCloud Data ServicesCloud InfrastructureCloud ManagementEnterprise SoftwareLife ScienceManagement Information SystemsMedical
Series AMar 14, 2019
Amount Raised: $5,000,000
Teckro

New York, New York, United States

Teckro is a life science technology company that is rethinking every element of clinical research.

ComputerInformation ServicesInformation TechnologyLife Science
Series CFeb 14, 2019
Amount Raised: $25,000,000
Evox Therapeutics

Oxford, Oxfordshire, United Kingdom

Evox Therapeutics is a biotechnology company that harnesses and engineer the natural trafficking capabilities of extracellular vesicles.

BiotechnologyHealth CarePharmaceutical
Series BSep 2, 2018
Amount Raised: $45,225,890
Compass Therapeutics, Inc.

Boston, Massachusetts, United States

Compass Therapeutics is a biopharmaceutical company that focuses on drugging the immune system to treat human diseases.

BiopharmaBiotechnologyTherapeutics
Series AJul 12, 2018
Amount Raised: $49,000,000