
Catalio Capital Management
Description
Catalio Capital Management is a New York-based venture capital firm that has rapidly established itself as a significant investor in breakthrough biomedical technology companies. Founded in 2020 by George Petrocheilos and Dr. R. Jacob Vogelstein, the firm specializes in identifying and nurturing innovative life sciences ventures across various stages, from early-stage venture to growth equity and even public markets. Their investment philosophy is deeply rooted in scientific expertise, often partnering with leading academic institutions and scientific innovators to commercialize cutting-edge research.
Catalio's strategy involves a multi-pronged approach, deploying capital through dedicated venture funds, growth equity funds, and public equity vehicles. This allows them flexibility to support companies throughout their lifecycle, providing not just capital but also strategic guidance and access to a vast network within the healthcare and biotech sectors. The firm is known for its commitment to long-term partnerships, aiming to build enduring companies that address critical unmet medical needs.
Demonstrating its rapid growth and strong market presence, Catalio Capital Management announced in March 2024 that its total assets under management (AUM) had surpassed $2.1 billion. This milestone was significantly bolstered by the successful closing of its third venture fund, Catalio Nexus Fund III, which secured $381 million in commitments. These substantial fund sizes enable Catalio to make meaningful investments in capital-intensive biomedical research and development, supporting the translation of scientific discoveries into tangible therapeutic and diagnostic solutions.
Their portfolio reflects a diverse range of companies engaged in areas such as gene therapy, precision medicine, oncology, and neuroscience. Catalio typically seeks to be a lead or co-lead investor, providing substantial initial capital and participating in subsequent funding rounds to support portfolio companies through critical development milestones. Their focus remains on companies poised to make a transformative impact on human health.
Investor Profile
Catalio Capital Management has backed more than 84 startups, with 15 new investments in the last 12 months alone. The firm has led 24 rounds, about 29% of its total and boasts 15 exits across its portfolio.
Investment Focus Highlights
- Concentrates on Series A, Series B, Series Unknown rounds (top funding stages).
- Majority of deals are located in United States, Switzerland, France.
- Strong thematic focus on Biotechnology, Health Care, Therapeutics.
- Led 2 rounds in the past year.
- Typical check size: $5M – $50M.
Stage Focus
- Series A (26%)
- Series B (25%)
- Series Unknown (14%)
- Series C (13%)
- Series D (7%)
- Post Ipo Equity (4%)
- Series E (4%)
- Seed (2%)
- Debt Financing (2%)
- Private Equity (1%)
Country Focus
- United States (89%)
- Switzerland (4%)
- France (2%)
- Germany (2%)
- Israel (1%)
- Australia (1%)
Industry Focus
- Biotechnology
- Health Care
- Therapeutics
- Medical
- Life Science
- Pharmaceutical
- Health Diagnostics
- Biopharma
- Medical Device
- Oncology
Frequently Asked Questions
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