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Astellas Venture Management

North America, California, United States, Menlo Park

Description

Astellas Venture Management (AVM) is the dedicated corporate venture capital arm of Astellas Pharma Inc., a leading Japanese multinational pharmaceutical company. Based in Menlo Park, California, AVM plays a crucial role in Astellas's long-term growth strategy by identifying and investing in innovative biotechnology and life sciences companies. Established in 2005, AVM's primary objective is to gain early access to cutting-edge science and technology that aligns with Astellas Pharma's therapeutic areas of interest, thereby complementing its internal research and development pipeline and fostering external innovation.

AVM's investment strategy is highly strategic, focusing on companies developing novel therapeutics, diagnostics, and platform technologies across a range of therapeutic areas. These include, but are not limited to, oncology, immunology, ophthalmology, neuroscience, and rare diseases, mirroring the parent company's core areas of focus. While they primarily target early-stage companies (Seed, Series A, and Series B rounds), AVM is flexible and will consider later-stage opportunities that present significant strategic value. Their geographic focus is predominantly North America and Europe, although they also engage with promising ventures in Japan and other global innovation hubs.

As a strategic investor, AVM provides more than just capital; they offer portfolio companies access to Astellas Pharma's extensive scientific expertise, development capabilities, and global network. This collaborative approach aims to accelerate the development of breakthrough therapies and technologies. AVM typically participates in funding rounds with initial investments ranging from $2 million to $10 million, though their total commitment to a company can grow significantly through follow-on rounds. For instance, they have participated in Series B rounds exceeding $100 million, demonstrating their capacity for substantial long-term engagement in promising ventures. Their consistent activity in the biotech funding landscape underscores their commitment to fostering innovation within the life sciences sector.

Investor Profile

Astellas Venture Management has backed more than 67 startups, with 3 new investments in the last 12 months alone. The firm has led 8 rounds, about 12% of its total and boasts 13 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series A, Series B, Series Unknown rounds (top funding stages).
  • Majority of deals are located in United States, United Kingdom, Japan.
  • Strong thematic focus on Biotechnology, Health Care, Therapeutics.
  • Led 1 rounds in the past year.
  • Typical check size: $2M – $10M.

Stage Focus

  • Series A (34%)
  • Series B (31%)
  • Series Unknown (18%)
  • Series C (6%)
  • Seed (4%)
  • Series D (3%)
  • Pre Seed (1%)
  • Series E (1%)

Country Focus

  • United States (66%)
  • United Kingdom (24%)
  • Japan (7%)
  • Canada (1%)
  • Switzerland (1%)

Industry Focus

  • Biotechnology
  • Health Care
  • Therapeutics
  • Medical
  • Pharmaceutical
  • Biopharma
  • Life Science
  • Genetics
  • Medical Device
  • Oncology
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does Astellas Venture Management frequently co-invest with?

Abingworth
Europe, England, United Kingdom, London
Co-Investments: 4
Amgen Ventures
North America, California, United States, San Francisco
Co-Investments: 5
Novartis Venture Fund
Europe, Basel-Stadt, Switzerland, Basel
Co-Investments: 13
Alexandria Venture Investments
North America, California, United States, Pasadena
Co-Investments: 4
MPM Capital
North America, Massachusetts, United States, Boston
Co-Investments: 12
Longwood Fund
North America, Massachusetts, United States, Boston
Co-Investments: 8
SR One
North America, Massachusetts, United States, Cambridge
Co-Investments: 5
OUP (Osage University Partners)
North America, Pennsylvania, United States, Bala Cynwyd
Co-Investments: 7
U.S. Venture Partners
North America, California, United States, Menlo Park
Co-Investments: 6
Sofinnova Partners
Europe, Ile-de-France, France, Paris
Co-Investments: 5

Which angels does Astellas Venture Management often collaborate with?

DD
Europe, Cambridgeshire, United Kingdom, Cambridge
Shared Deals: 1
JM
North America, Massachusetts, United States, Cambridge
Shared Deals: 4

What are some of recent deals done by Astellas Venture Management?

Solu Therapeutics

Boston, Massachusetts, United States

Solu Therapeutics Platform Company that develops antibody-based medicines using a degradable warhead.

BiotechnologyMedicalTherapeutics
Series AApr 9, 2025
Amount Raised: $41,000,000
SyntaxBio

Chicago, Illinois, United States

SyntaxBio develops genetic programming platform that can program cells without the need for consistent external intervention.

BiotechnologyMedicalProduct Research
SeedSep 17, 2024
PhoreMost

Cambridge, Cambridgeshire, United Kingdom

PhoreMost is a new-model drug discovery company based in Cambridge, UK.

BiopharmaBiotechnologyHealth Care
Series BSep 12, 2024
Amount Raised: $12,000,000
NeoPhore

Cambridge, Cambridgeshire, United Kingdom

NeoPhore is a provider of novel small molecule therapies intended to treat cancer through stimulation of the immune system.

BiotechnologySimulationTherapeuticsTranslation Service
Series BFeb 1, 2024
Amount Raised: $12,236,423
Shinobi Therapeutics

South San Francisco, California, United States

Shinobi Therapeutics develops immune-evasive iPS cell therapies for cancer treatment.

BiotechnologyHealth CareTherapeutics
Series ADec 12, 2023
Amount Raised: $51,000,000
Mogrify

Cambridge, Cambridgeshire, United Kingdom

Mogrify® will transform the lives of patients with degenerative diseases through a novel class of in vivo reprogramming therapies.

Big DataBioinformaticsBiotechnologyHealth CareLife ScienceTherapeutics
Series AOct 2, 2023
Amount Raised: $10,000,000
Solu Therapeutics

Boston, Massachusetts, United States

Solu Therapeutics is a precision-medicine-focused company developing therapeutics to eliminate disease-driving cells.

BiotechnologyTherapeutics
SeedAug 1, 2023
Amount Raised: $31,000,000
Avilar Therapeutics

Waltham, Massachusetts, United States

Avilar Therapeutics is a biopharmaceutical company focusing on extracellular protein degradation.

BiotechnologyMedicalPharmaceutical
SeedFeb 16, 2023
Amount Raised: $15,000,000
NeoPhore

Cambridge, Cambridgeshire, United Kingdom

NeoPhore is a provider of novel small molecule therapies intended to treat cancer through stimulation of the immune system.

BiotechnologySimulationTherapeuticsTranslation Service
Series BJan 19, 2023
Amount Raised: $7,435,460
Casma Therapeutics

Cambridge, Massachusetts, United States

Casma Therapeutics is a biotechnology company harnessing the natural cellular process of autophagy to design new medicines.

BiotechnologyHealth CareTherapeutics
Series CNov 15, 2022
Amount Raised: $46,000,000