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TPG Biotech

North America, California, United States, San Francisco

Description

TPG Biotech is a specialized investment platform operating under the umbrella of TPG Capital, a leading global alternative asset firm. Based in San Francisco, it is dedicated to providing growth-stage equity and venture capital to companies within the dynamic biotechnology industry. This platform leverages TPG's extensive resources and deep expertise in healthcare to identify and support innovative companies poised for significant impact and commercialization.

The platform's investment strategy is focused on companies developing novel therapeutics, diagnostics, and medical devices that address unmet medical needs. TPG Biotech typically engages with companies that are beyond the very early stages, often providing capital for critical phases such as clinical development, regulatory approval, and market commercialization. Their involvement often extends to strategic guidance, operational support, and leveraging TPG's vast network to accelerate portfolio company growth.

As part of TPG Capital's robust healthcare investment practice, TPG Biotech benefits from a long history of significant capital deployment in the sector. TPG Capital has collectively invested over $20 billion across more than 70 healthcare companies globally, demonstrating a profound commitment to the industry. For TPG Biotech's specific investments, typical first check sizes can range from approximately $25 million for later-stage venture opportunities to upwards of $200 million for substantial growth equity rounds, reflecting their capacity to lead or co-lead significant financings. This broad range allows them to support a diverse set of companies requiring substantial capital to scale.

Investor Profile

TPG Biotech has backed more than 73 startups, with 1 new investments in the last 12 months alone. The firm has led 22 rounds, about 30% of its total and boasts 23 exits across its portfolio.

Investment Focus Highlights

  • Concentrates on Series B, Series C, Series A rounds (top funding stages).
  • Majority of deals are located in United States, Canada, Israel.
  • Strong thematic focus on Biotechnology, Health Care, Medical.
  • Typical check size: $25M – $200M.

Stage Focus

  • Series B (30%)
  • Series C (25%)
  • Series A (21%)
  • Series D (10%)
  • Private Equity (5%)
  • Series Unknown (4%)
  • Post Ipo Equity (1%)
  • Series E (1%)
  • Series F (1%)
  • Series G (1%)

Country Focus

  • United States (88%)
  • Canada (4%)
  • Israel (4%)
  • Philippines (1%)
  • Japan (1%)
  • Denmark (1%)

Industry Focus

  • Biotechnology
  • Health Care
  • Medical
  • Pharmaceutical
  • Biopharma
  • Therapeutics
  • Medical Device
  • Health Diagnostics
  • Life Science
  • Software
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FAQ

Frequently Asked Questions

Learn who this investor regularly partners with—both firms and angels—and explore their latest activity.

Who does TPG Biotech frequently co-invest with?

OrbiMed
North America, New York, United States, New York
Co-Investments: 9
Claremont Creek Ventures
North America, California, United States, Oakland
Co-Investments: 5
Domain Associates
North America, California, United States, San Diego
Co-Investments: 9
Kleiner Perkins
North America, California, United States, Menlo Park
Co-Investments: 10
New Enterprise Associates
North America, California, United States, Menlo Park
Co-Investments: 5
RiverVest
North America, Missouri, United States, St Louis
Co-Investments: 6
Novo Ventures
Europe, Hovedstaden, Denmark, Bagsværd
Co-Investments: 9
Longitude Capital
North America, California, United States, Menlo Park
Co-Investments: 5
OUP (Osage University Partners)
North America, Pennsylvania, United States, Bala Cynwyd
Co-Investments: 5
HealthCap
Europe, Stockholms Lan, Sweden, Stockholm
Co-Investments: 9

Which angels does TPG Biotech often collaborate with?

John Livingston
North America, British Columbia, Canada, Vancouver
Shared Deals: 1

What are some of recent deals done by TPG Biotech?

Avalyn Pharma

Seattle, Washington, United States

Avalyn Pharma is a biopharma company developing therapies for the treatment of idiopathic pulmonary fibrosis and other respiratory diseases.

BiopharmaBiotechnologyMedicalPharmaceutical
Series DJul 22, 2025
Amount Raised: $100,000,000
ADCendo

Copenhagen, Hovedstaden, Denmark

ADCendo ApS is a biotech company dedicated to developing new types of anti-cancer drugs.

BiotechnologyHealth Care
Series BNov 25, 2024
Amount Raised: $135,000,000
Carisma Therapeutics

Philadelphia, Pennsylvania, United States

Carisma Therapeutics is a biotech company that develops novel chimeric antigen receptor macrophage technology to treat solid tumors.

BiotechnologyHealth CareLife ScienceMedicalTherapeutics
Series CSep 21, 2022
Amount Raised: $30,000,000
Carisma Therapeutics

Philadelphia, Pennsylvania, United States

Carisma Therapeutics is a biotech company that develops novel chimeric antigen receptor macrophage technology to treat solid tumors.

BiotechnologyHealth CareLife ScienceMedicalTherapeutics
Series BMar 1, 2021
Amount Raised: $12,000,000
Carisma Therapeutics

Philadelphia, Pennsylvania, United States

Carisma Therapeutics is a biotech company that develops novel chimeric antigen receptor macrophage technology to treat solid tumors.

BiotechnologyHealth CareLife ScienceMedicalTherapeutics
Series BJan 7, 2021
Amount Raised: $47,000,000
Azura Ophthalmics

Tel Aviv, Tel Aviv, Israel

Azura Ophthalmics is a clinical-stage company that develops an innovative portfolio of compounds to advance treatments for MGD.

BiotechnologyHealth CareMedical
Series COct 22, 2020
Amount Raised: $20,000,000
DNAnexus

Mountain View, California, United States

DNAnexus develops a cloud platform and global network designed for scientific collaboration and accelerated discovery.

BioinformaticsBiotechnologyCloud ComputingMedicalSoftware
Series GJun 9, 2020
Amount Raised: $100,000,000
Avalyn Pharma

Seattle, Washington, United States

Avalyn Pharma is a biopharma company developing therapies for the treatment of idiopathic pulmonary fibrosis and other respiratory diseases.

BiopharmaBiotechnologyMedicalPharmaceutical
Series BApr 27, 2020
Amount Raised: $35,500,000
Satsuma Pharmaceuticals

South San Francisco, California, United States

Satsuma Pharmaceuticals is a clinical-stage biopharmaceutical company engaged in developing a novel therapeutic product.

BiotechnologyHealth CarePharmaceuticalTherapeutics
Series BApr 24, 2019
Amount Raised: $62,000,000
Fusion Pharmaceuticals

Hamilton, Ontario, Canada

Fusion Pharmaceuticals is a clinical-stage oncology company focused on developing radiopharmaceuticals.

BiopharmaBiotechnologyMedicalOncologyPharmaceutical
Series BApr 1, 2019
Amount Raised: $105,000,000